摘要
目的:探讨中药敏咳煎对咳嗽变异性哮喘(CVA)患者咳嗽敏感性(CRS)的影响,并引入莱切斯特咳嗽问卷(LCQ)对患者的生活质量进行评估。方法:62例中医辨证为阴虚肺燥的CVA患者随机分为治疗组和对照组,治疗组采用中药敏咳煎治疗,对照组采用美普清(盐酸丙卡特罗)治疗,均治疗2周。观察治疗前、后患者CRS的变化情况,并用LCQ评估治疗前、后生活质量的变化。结果:治疗2周后,中药治疗组患者CRS治疗前、后比较差异有统计学意义(P<0.05);对照组患者CRS治疗前、后比较差异无统计学意义(P>0.05);两组患者治疗前、后LCQ评估差异均有统计学意义(P<0.05),中药治疗组LCQ改善幅度明显大于对照组(P<0.01)。结论:中药敏咳煎能降低CVA患者CRS水平,改善LCQ评分,从而从根本上缓解咳嗽症状,改善患者生活质量。
Objective：To observe the influence of therapeutid treatment based on Minkefian on cough reflex sensitivity in pa- tients with cough variant asthma and use the Leicester Cough Questionnaire to evaluate life quality. Methods ： Sixty-two patients with CVA diagnosed as yin deficiency and lung dryness syndrome according to TCM theories were randomly divided into the treat- ment group and control group. The treatment group was treated with Mirtkejian and the control group was treated with procaterol hydrochloride. Both groups were treated for 2 weeks. The changes of CRS and the LCQ were observed before and after treatment. Results ： Compared with the result before treatment, CRS of the treatment group was decreased after 2 weeks treatment（ P 〈 0. 05 ）. While the change of CRS in control group had no statistical significance（ P 〉 O. 05 ）. Compared with the result before treatment, the scores of LCQ in both two groups were increased after treatment （ P 〈 0. 05 ）. And scores in the treatment group can be in- creased significantly greater than that in the control group with statistical significance （P 〈 0. 01 ）. Conclusion：Minkejian can de- crease patients with CVA on CRS for remission of cough symptoms and improve life quality.
出处
《辽宁中医杂志》
CAS
2013年第5期927-929,共3页
Liaoning Journal of Traditional Chinese Medicine
关键词
敏咳煎
咳嗽敏感性
莱切斯特咳嗽问卷
生活质量
Minkejian
cough reflex sensitivity
Leicester Cough Questionnaire
life quality
