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反义寡核苷酸对HCV5′NCR基因调控功能的特异性抑制作用 被引量:3

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出处 《中华微生物学和免疫学杂志》 CSCD 北大核心 2000年第5期436-437,共2页 Chinese Journal of Microbiology and Immunology
基金 国家"8 6 3"资助!(10 2 0 8 0 4 0 1) 国家自然科学基金! (395 0 0 179) 军队"9.5"重点课题 !(96Z0 0 7)
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  • 1BukhJ Purcell RH Miller RH.Sequence analysis of the 5′noncoding region of hepatitis C virus[J].Proc Natl Acad Sci USA,1992,89(11):4942-4946.
  • 2[2]Martell M, Gomez J, Esteban J I, et al. High-thoughput real-time reverse transcription PCR quantitation of hepatitis C virus RNA[J]. J Clin Microbiol, 1999, 37(2): 327 - 332.
  • 3[3]Seki M, Honda Y. Phosphorothioate antisense oligodeoxynucleotides capable of inhibiting hepatitis C virus gene expression, in vitro translation assay [J]. J Biochem (Tokyo), 1995, 118(6): 1199- 1204.
  • 4Manns MP, McHutchison JG, Gordon SC, et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial[J]. Lancet, 2001, 358(9286) :958-965.
  • 5Rijinbrand R, Bredenbeek PJ, Haasnoot PC, et al. The influence of downstream protein-coding sequence on internal ribosome entry on hepatitis C virus and other flavivirus RNAs[J]. RNA,2001, 7(4) :585-597.
  • 6Bukh J, Purcell RH, Miller RH. Sequence analysis of the 5 'noncoding region of hepatitis C virus[J]. Proc Natl Acad Sci USA,1992,89 ( 11 ) :4942 -4946.
  • 7Wang C, Sarnow P, Siddiqui A. Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosomebinding mechanism[J]. J Virul, 1993, 67(6) :3338-3344.
  • 8Alt M, Renz R, Hofschneider PH, et al. Specific inhibition of hepatitis C viral gene expression by antisense phosphorothioate oligodexynucleotides[J]. Hepatology, 1995, 22 (3) :709-717.
  • 9Wang C, Sarnow P, Siddiqui A. Translation of human hepatitisC virus RNA in cultured cells is mediated by an internal ribosome2binding mechanism (J). J Virol, 1999,67(6):3338-3344.
  • 10Alt M, Renz R, Hofschneider PH, et al. Specific inhibition of hepatitis C viral gene expression by antisense hosphorothioate oligo dexynucleotides (J). Hepatology, 2002, 22(3):709-717.

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