摘要
应用暴露限值法(MOE,margin of exposure)评估黄曲霉毒素暴露风险。在取样检测我国产后花生黄曲霉毒素污染浓度数据和收集整理花生消费数据以及毒理学资料基础上,应用MOE法评估我国不同地区(城市和农村)、不同年龄组人群膳食摄入黄曲霉毒素的致癌风险。评估结果显示:城市和农村人群膳食摄入黄曲霉毒素致癌风险无显著差异,儿童属于高风险人群。与低剂量外推方法相比,MOE法计算结果更便于后期应用。MOE法值得在黄曲霉毒素等遗传毒性致癌物风险评估中推广应用。
To explore the MOE （margin of exposure） application in risk assessment of peanut aflatoxins in consumers, data of aflatoxins contamination in post-harvest peanut of China and the data of Chinese peanut consumption were collected. Based on aflatoxins toxicological data, MOE values of different regions from population of different age-groups were evaluated. Results indicated no significant difference between urban and rural regions, but children were at higher risk than other populations. Compared to low-dose extrapolation, MOE was recommended due to its effective performance in posterior analysis.
出处
《中国油料作物学报》
CAS
CSCD
北大核心
2013年第2期211-216,共6页
Chinese Journal of Oil Crop Sciences
基金
无公害农产品质量安全监测普查项目
农产品质量安全风险评估项目
公益性行业(农业)科研专项(201303088)
湖北省自然科学基金(2011CDB356)
中国农业科学院油料作物研究所所长基金(1610172011013)
国家科技支撑计划(2012BAB19B09)
