摘要
目的 研究四倍体菘蓝IsatisindigoticaFort.根的化学成分。 方法 应用硅胶柱色谱对乙酸乙酯萃取部分中化学成分进行分离纯化 ,根据理化常数测定和光谱 (IR ,MS ,1HNMR ,13CNMR ,2DNMR)分析技术鉴定结构。结果 从乙酸乙酯萃取部位分离得到 4种生物碱类化合物 ,分别鉴定为 :色胺酮 (I) ,2 ,5 二羟基吲哚 (II) ,2 ,3 二氢 4 羟基 2 氧 吲哚 3 乙腈 (III) ,吲哚 3 乙腈 6 O β D 葡糖苷 (IV)。结论 II为首次从该种植物中分离得到 ,III。
AIM Investigating the chemical constituents of tetraploidy Banlangen( Isatis indigotica Fort). METHODS Compounds were separated by chromatography on silica gel. Their structures were determined by spectral analysis and chemical evidence. RESULTS Four alkaloids were isolated. Their structures were identified as trytanthrin (I), 2,5 dihydroxy indole(II), 2,3 dihydro 4 hydroxy 2 oxo indole 3 acetonitrile(III) and indole 3 acetonitrile 6 O β D glucopyranoside(IV). CONCLUSION Compounds III and IV are new compounds.
出处
《药学学报》
CAS
CSCD
北大核心
2000年第7期508-510,共3页
Acta Pharmaceutica Sinica
基金
国家自然科学基金资助项目!(39670878)
关键词
四倍体板蓝根
化学成分
中药
生物碱
tetraploidy
Banlangen
2,3-dihydro-4-hydroxy -2-oxo-indole-3-acetonitrile
indole-3-acetonitrile -6-o-β-D- glucopyranoside
