摘要
目的 :观察 70岁以上老年急性心肌梗死 (AMI)的静脉溶栓疗效。方法 :35例 70岁以上 AMI患者(病例组 )采用尿激酶静脉溶栓 ,与同期 42例≤ 6 9岁的 AMI患者作对照。观察患者末梢血嗜酸粒细胞计数及血液皮质醇含量 ,比较 2组再通率及溶栓后并发症发生率。结果 :老年 AMI患者末梢血嗜酸粒细胞计数减少 ,血皮质醇升高。 2组患者 49小时以上溶栓者 5例 ,无一例再通。 2组 12小时内溶栓再通率无明显差异 ,溶栓后并发症发生率无显著性差异。结论 :对老年 AMI患者静脉溶栓仍是安全有效的治疗方法 ;年龄不是静脉溶栓疗法的严格限制因素 ;AMI静脉溶栓的时间窗可以限制在
Objective:To observe the curative effects of intravenous thrombolysis on senile patients with acute myocardial infarction(AMI) aged more than 70.Methods:Thirtyfive cases with AMI aged more than 70(treated group)were treated with intravenous thrombolysis using urokinase and at the same time 42 cases aged less than 69 were choosen as control group.The eosinophil granulocyte count in periphral blood and the concentrations of cortisol in blood in patients were observed.The recanalization rate and occurrance rate of complications after thrombolysis in two groups were compared.Results:The eosinophil granulocyte count in senile patients was decreased but the concentration of cortisol was hightened.In two groups among 5 cases who received intravenous thrombolysis over 49 hours after attack of AMI no one was repatency.The recanalization rates in two groups had not obvious difference if the thromolysis was carried out within 12 hours meanwhile the occurrance rates of complications after thrombolysis had not marked difference too.Conclusions:The treatment with intravenous thrombolysis for senile patients with AMI is still safe and effective.The age is not a strict factor to limit the use of intravenous thrombolysis.The timewindow of thrombolysis for patients with AMI should be restricted in 36 hours.
出处
《中国中西医结合急救杂志》
CAS
2000年第5期284-285,共2页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
基金
辽宁省科委 2 0 0 0年度科研课题
关键词
心肌梗死
静脉溶栓
老年人
嗜酸粒细胞
皮质醇
acute myocardial infarction
intravenous thrombolysis
senile
eosinophil granulocyte
cortisol
