摘要
目的 探讨双歧杆菌三联活菌散（培菲康）治疗小儿肺炎继发腹泻的临床疗效,寻找小儿肺炎继发腹泻的相关因素.方法 选择385例肺炎患儿作为研究对象,筛选肺炎继发腹泻的相关因素；120例肺炎继发腹泻患儿按随机数字表法分为观察组和对照组,每组60例,观察组给予培菲康联合常规治疗,对照组仅给予常规治疗,治疗7d后评价临床疗效.结果 观察组总有效率为96.7％（58/60）,对照组为61.7％（37/60）,两组比较差异有统计学意义（x^2=22.282,P＜ 0.01）.发病年龄、住院时间、侵入性操作、联合抗生素使用、激素使用、微生态制剂（培菲康）使用与小儿肺炎继发腹泻有关（P＜ 0.01或＜0.05）.结论 年龄小、住院时间长、侵入性操作、联合抗生素使用、激素使用是小儿肺炎继发腹泻的危险因素.采用培菲康治疗小儿肺炎继发腹泻疗效确切,值得临床上推广应用.
Objective To investigate the clinical effect of live combined bifidobacterium,lactobacillus and enterococcus powder （probiotics bifico） treatment in children with secondary diarrhea of pneumonia and analysis of related factors.Methods Three hundred and eighty-five pneumonia children were studied.The related factors of secondary diarrhea of pneumonia were screened.One hundred and twenty cases of children with secondary diarrhea of pneumonia were divided into observation group and control group by table of random digit with 60 cases each.The observation group was given the probiotics bifico combined with conventional treatment,the control group was given the conventional treatment.The clinical efficacy was evaluated treatment after 7 d.Results The effective rate of observation group was significantly higher than that of control group [96.7%（58/60） vs.61.7%（37/60）,x^2 =22.282,P〈 0.01].Age of onset,hospitalization time,invasive procedures,combination therapy of antibiotics,therapy of hormone and therapy of probiotics bifico were related with the incidence of secondary diarrhea of pneumonia （P 〈 0.01 or 〈 0.05）.Conclusions The younger children,long hospital stay,invasive procedures,combination therapy of antibiotics and therapy of hormone are the risk factors of secondary diarrhea of pneumonia.The probiotics bifico for treating the children with secondary diarrhea of pneumonia has exact clinical efficacy,and it is worthy of clinical application.
出处
《中国医师进修杂志》
2013年第12期33-35,共3页
Chinese Journal of Postgraduates of Medicine
关键词
肺炎
腹泻
儿童
Pneumonia
Diarrhea
Child
