摘要
目的探讨输血前对患者常规开展不规则抗体筛查的意义。方法对5761例受检者标本采用微柱凝胶技术进行不规则抗体筛查,对抗体筛选阳性的标本进一步鉴定其特异性。结果共鉴定确认为不规则抗体14例,不规则抗体检出率0.24%。其中,抗E抗体4例(28.57%),抗D抗体3例(21.43%),抗S抗体1例(7.14%),抗M抗体3例(21.43%),抗H抗体1例(7.14%),抗Lea抗体1例(7.14%),抗Ce抗体1例(7.14%)。结论对有输血史(尤其是多次输血者)、妊娠、正反定型不符、交叉配血不合的患者和献血者进行不规则抗体筛查,可避免血型抗体引起的溶血反应,从而保障安全输血。
Objective To investigate the clinical significance of screening irregular antibody before blood transfusion. Methods The detection of irregular antibodies was performed using microcolumn gel technique in 5761 subjects. The specificity of samples with positive antibody screen was further identified. Results A total of 14 cases was confirmed to have irregular antibodies and the detection rate for irregular antibodies was 0. 24%. Of 14 cases,4 ~ases（28. 57%） had anti-E antibody, 3 cases（21.43%） had anti-D, 1 case（7.14%） had anti-S, 3 cases（21.43%） had anti-M, 1 case （7.14%） had anti-H,1 case（7. 14%） had anti-Lea,and 1 case（7. 14%） had anti-Ce. Conclusion To guarantee the safety of blood transfusion, screening the irregular antibodies before blood transfusion can avoid blood transfusion-related adverse responses such as hemolytic reaction induced by irregular antibodies in the patients and blood donors with a history of blood transfusion（especially with multiple blood transfusions）,pregnancy, immatched positive and negative stereotypes or cross matching.
出处
《江苏医药》
CAS
北大核心
2013年第8期951-952,共2页
Jiangsu Medical Journal
关键词
不规则抗体
输血
溶血
Irregular antibodies
Blood transfusion
Hemolysis
