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异基因造血干细胞移植治疗骨髓增生异常综合征的时机选择 被引量:1

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摘要 骨髓增生异常综合征(myelodysplastic syndrome,MDS)是造血干细胞性克隆性疾病,主要表现为贫血、出血和严重感染,并具有向急性白血病转化的危险性。在过去的数十年中,虽然很多新药应用于临床,然而迄今为止,异基因造血干细胞移植仍然是治愈MDS的唯一手段,而干细胞移植的时机是人们争论的焦点。作者从发病到移植的时间、疾病缓解情况及去甲基化治疗药物在异基因造血干细胞移植治疗MDS中的应用三个方面作一综述。
出处 《现代医学》 2013年第4期279-281,共3页 Modern Medical Journal
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