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米托蒽醌长循环脂质体的制备及特性 被引量:1

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摘要 目的通过对米托蒽醌长循环脂质体的制备,达到一种高效的抗癌治疗作用。方法采用逆相蒸发法以DSPCDSPE-34HCSI胆固醇为原料,制备了米托蒽醌空间稳定多相脂质体。并对其粒径、分布、载药量、包封率及在小鼠体内分布进行了测定。结果米托蒽醌长循环脂质体在体内循环时间延长,肝、肺脏分布增高。结论对增强其抗癌效果和降低毒副作用具有一定意义。
出处 《中国疗养医学》 2013年第4期363-364,共2页 Chinese Journal of Convalescent Medicine
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共引文献23

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