摘要
目的比较非血液系统恶性肿瘤患者化疗前后血液流变学的变化趋势,并探讨留置PICC导管对非血液系统肿瘤化疗患者血液流变学的影响。方法分别测定37例留置PICC导管(试验组)及36例未留置PICC导管(对照组)非血液系统恶性肿瘤患者化疗前后血液流变学指标,观察化疗后的血液流变学变化趋势,并对两组患者的血液流变学指标进行比较分析。结果对照组化疗后全血黏度值(切变率1、5、50、100、200s-1)、全血低切相对指数、全血高切相对指数、全血低切还原黏度、全血高切还原黏度、红细胞刚性指数均低于化疗前(P<0.05);试验组化疗后所有血液流变学指标与化疗前比较,差异均不具有显著性(P>0.05);试验组化疗后所有血液流变学指标与对照组化疗后比较,差异均不具有显著性(P>0.05)。结论留置PICC导管对非血液系统恶性肿瘤化疗患者血液流变学没有影响。
【Objective】To study the trends in blood rheology in patients with malignant tumor after chemotherapy and to explore the effect of PICC on hemorheology in patients with non-hematologic malignancies chemotherapy.【Methods】Were measured in 37 cases PICC（the experimental group） and 36 cases did not undergo（the control group） hemorheological changes in patients with non-hematologic malignancies before and after chemotherapy,observation the non-hematologic malignancies patients after chemotherapy changes in the hemarheology trends,and the situation of the hemorheology changes in patients with non-hematologic malignancies were compared between the two groups.【Results】The control group after chemotherapy,great majority hemorheological indicators were lower than those before chemotherapy（P 0.05）;there were no hemorheological indicators differences between before and after chemotherapy in the group of row PICC（P 0.05）;there were no hemorheological indicators differences between the two groups of patients after chemotherapy（P 0.05）.【Conclusion】Rowed PICC on blood rheology have no effect in chemotherapy patients with non-hematologic malignancies.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2013年第6期102-105,共4页
China Journal of Modern Medicine
基金
湖南省科技厅资助(No:2010SK3107)
