摘要
目的:探讨液基细胞学检查(TCT)诊断配合阴道镜宫颈活检对宫颈上皮内瘤样病变(CIN)的诊断价值。方法:对165例行TCT筛查阳性患者行阴道镜宫颈活检,采用TBS分级系统进行诊断,并与病理结果进行比较。结果:123例经TCT诊断为ASCUS患者中,诊断为CIN 61例,与阴道镜宫颈活检符合率为49.6%(CINⅠ50例,CINⅡ8例,CINⅢ3例);29例LTC诊断为HSIL患者中,诊断为CIN21例,与阴道镜宫颈活检符合率为72.4%(CINⅠ11例,CINⅡ8例,CINⅢ2例);12例TCT诊断为LSIL患者中,诊断为CIN 8例,与阴道镜宫颈活检符合率为66.7%(CINⅠ5例,CINⅡ2例,CINⅢ1例);TCT诊断为SCC的1例患者,诊断为浸润癌,与阴道镜宫颈活检符合率为100.0%。结论:TCT配合阴道镜宫颈活检诊断宫颈病可以降低漏诊率,是宫颈癌前病变简单有效的诊断方法,值得临床推广应用。
Objective： To study the value of liquid--based cytology （TCT） test combined with col- poscopic cervical biopsy for diagnosis of cerivical intraepithelial neoplasia （CIN）. Methods： Among 165 ca- ses that underwent regular TCT test screening up, those who were diagnosed as positive underwent eolpo- scopic cervical biopsy for further diagnosis by TBS classification system, and the TCT test results were compared with colposcopic cervical biopsy results. Results： Sixty-one of the 123 cases that were diagnosed as ASCUS were diagnosed as CIN, showing accuracy rate of 49. 6% according to colposcopic cervical biop- sy results （50 cases CIN I , 8 cases CIN Ⅱ and 3 cases CINⅢ） ; of the 29 cases that were diagnosed as HSIL according to TCT, 21 cases were diagnosed as CIN, showing accuracy rate of 72. 4% according to eolposcopic cervical biopsy results （11 eases CIN I , 8 eases CIN Ⅱ and 2 eases CINⅢ ）; of the 12 eases that were diagnosed as LSIT according to TCT 8 were diagnosed as CIN, showing accuracy rate of 72.4 according to colposcopic cervical biopsy results, One ease was diagnosed as SCC, which is confirmed by col- poscopie cervical biopsy results. Conclusion： The liquid--based cytology test combined with colposcopic cervical biopsy can avoid misdiagnosis, it is a simple and effective diagnostic method for the cervical pre- cancerous lesions, and is worthy of clinical application.
出处
《海南医学院学报》
CAS
2013年第4期539-541,共3页
Journal of Hainan Medical University
基金
中国高校医学期刊临床专项资金项目(112210610)~~
关键词
液基细胞学检查
阴道镜宫颈活检
宫颈上皮内瘤变
Liquid-based cytology
Colposcopic cervical biopsy
Cerivical intraepithelial neoplasia
