摘要
目的观察四磨汤口服液治疗小儿消化不良的临床疗效观察，并探究其作用机制。方法将所选取的90例消化不良患儿分为对照组和观察组，每组45例，对照组口服多潘立酮片，观察组口服四磨汤口服液，观察两组的临床治疗有效率和治疗前后患者胃排空功能、症状和血浆P物质、胃动素的水平。结果两组临床有效率分别为70．0％、94．O％，对照组和观察组的胃排空总有效率分别为74．0％、80．0％，差异无统计学意义（P〉0．10），两组治疗前后组内的血浆P物质、胃动素含量差异有统计学意义（P〈0．05），但是治疗后组间差异无统计学意义（P〉0．05）。结论四磨汤口服液是治疗消化不良安全有效的中成药，其作用机制初步探究为能够促进胃排空、调节P物质、胃动素，为临床上消化不良的治疗提供了一定的参考意义。
Objective To observe and explore the clinical curative effect and mechanism of four grinding soup oral liquid in treating pediatric indigestion. Methods 90 children with indigestion were randomly divided into control group and observation group, and 45 people in each group. Children in control group were given Pan Li ketone tablet and the observation group were given four grinding soup oral liquid to observe the clinical curative effect of the two groups and gastric emptying function, symptoms and plasma substance P, motilin levels of patients before and after treating. Results The clinical efficient of Pan Li ketone tablet and four grinding soup oral liquid were 70.0% and 94. 0% respectively. The total effective rate of tgastric emptying of the control group and observation group of were 74.0% and 80.0%, and there were no significant difference （P 〉 0.10）. The plasma substance P, and motilin content of the two groups before and after treatment had significant difference（P 〈0.05 ） ,but there was no significant difference （ P 〉 0.05 ） between group after treating; Conclusion Four Grinding Soup oral liquid is a safe and effective way in treating pediatric indigestion, and it can promote gastric emptying function, plasma substance P and motilin levels, which provides certain reference significance for treating clinical indigestion.
出处
《中国基层医药》
CAS
2013年第5期693-695,共3页
Chinese Journal of Primary Medicine and Pharmacy
关键词
四磨汤
小儿消化不良
临床疗效
作用机制
Four grinding Soup
Pediatric indigestion
Clinical curative effect
Mechanism of action
