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庆大霉素毒性作用对肝肾的影响及其保护的形态学研究 被引量:8

Morphological Studies of Toxitic Effects of Gentamicin to Livers and Kidneys and its Protective Function
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摘要 通过肌注庆大霉素使豚鼠出现毒性损害 ,同时以碱性成纤维细胞生长因子作为拮抗剂 ,观察庆大霉素毒性作用对肝肾的形态学影响及其碱性成纤维细胞生长因子的保护作用。结果表明 By injecting gentamicin into guinea pig muscularly, toxitic damages were caused. On the same time, basic Fibroblast Growth Factor (bFGF) were used as antagonist agents. Morphological influences of toxitic effects gentamicin to livers and kidneys and protective effects of bFGF were observed. The results showed that bFGF had antagonistic effects to nephrotoxity caused by Gentamicin to a certain degree.
出处 《解剖科学进展》 CAS 2000年第3期260-263,共4页 Progress of Anatomical Sciences
关键词 庆大霉素 肾毒性 BFGF 对抗作用 豚鼠 gentamicin nephrotoxity bFGF antagonistic effects guinea pig
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