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筛选EGFR-TKI治疗非小细胞肺癌受益者生物标志物新进展 被引量:3

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摘要 近年来,临床上以吉非替尼(gefitinib)及厄洛替尼(erlotinib)为代表的EGFR-TKI在治疗非小细胞肺癌(NSCLC)患者生存率方面显示出令人满意的效果.但是EGFR—TKI的疗效在不同个体中差异较大。因此,筛选EGFR.TKI治疗NSCLC受益者生物标志物是当前亟待解决的课题。
出处 《实用医学杂志》 CAS 北大核心 2013年第7期1035-1036,共2页 The Journal of Practical Medicine
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  • 1Matsuo K, Ho H, Yatabe Y, et al. Risk factor differ for non- small-cell lung cancer with and without EGFR mutation: assessment of smoking and by a case-control study in Japanese [J]. Cancer Sci, 2010, 98(1):96-101.
  • 2Bell D W, Lynch T J, Haserlat S M, et al. Epidermal growth factor receptor mutations and gene amplification in lion small- cell lung caner:mohedar analysis of the 1DEAL/INTACT gefitinib mals [J]. J Clin Oncol, 2010, 23(31):8081-8092.
  • 3Kishore U, Greenhough T J, Waters P, et al. Surfactant proteins SP-A and SP-D: structure, function, and receptors [J]. Mol Immunol, 2009, 43( 1 ) : 1293-1315.
  • 4Yamaguchi H, Soda H, Nakamura Y, et al. Serum levels of surfactant protein D predict the anti-tumor activity of gefitinib in patients with advanced non-small cell lung cancer [J]. Cancer Chemother Pharmacol, 2010, 4(1) :41-47.
  • 5Italiano A, Cortot A B, Ilie M, et al. EGFR and KRAS status of primary sarcomatoid carcinomas of the lung: implications for anti-EGFR treatment of a rare lung malignancy [J]. Int J Cancer, 2010, 125(10):2479-2482.
  • 6Eberhard D A, Johnson B E, Amler L C, et al. Mutations in the epidermal growth factor receptor and in KRAS arepredictive and prognostic indicators in patients with non-small- cell lung cancer treated with chemotherapy alone and in combination with erlotinib[J]. J Clin Oncol, 2010, 23(25): 5900-5909.
  • 7Wang S, An T, Wang J, et al. Potential clinical significance of a plasma-based kras mutation analysis in patients with advanced non-small cell lung cancer [J]. Clin Cancer Res, 2010, 16(4) : 1324-1330.
  • 8Massarelli E, Varella-Garcia M, Tang X, et al. KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inbibitors in non-small cell lung cancer [Jl. Clin Cancer Res, 2009, 13 (10) :2890- 2896.
  • 9Kwak E L, Sordella R, Bell D W, et al. Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib [J]. Proc Natl Acad Sci, 2010, 102(2) :7665-7670.
  • 10Hirsch F R, Varella-Garcia M, Bunn Jr P A, et al. Molecular predictors of outcome with gefitinib in phase llI placebo- controlled study in advanced non-small-cell lung cancer [J]. J Clin Oncol, 2010, 24(3):5034-5042.

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