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纳洛酮治疗早产儿呼吸暂停的临床疗效观察 被引量:2

Effects of naloxone injection on apnea in preterm infants
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摘要 目的:观察纳洛酮治疗早产儿原发性呼吸暂停的疗效。方法:收集本院新生儿护理抢救中心2010年6月-2012年6月收治的72例早产儿,随机分为治疗组36例,对照组36例,对照组采取常规治疗,治疗组在常规治疗的基础上加用纳洛酮治疗。结果:治疗组显效率(69.4%)及总有效率(88.9%)均高于对照组,P<0.01。结论:纳洛酮针对病因治疗,对早产儿呼吸暂停有治疗和预防双重作用,早产儿呼吸暂停值得应用纳洛酮。 Objective:To asses the efficacy of naloxone injection on apnea in preterm infants. Methods: A total of 72 preterm infants were recruited from the intensive care unit of Duanzhou Maternal and Children' s Care Hospital, between June 2010 and June 2012, and were assigned to receive either usual treatment (n=-36) or the combination with naloxone ( n = 36 ). Results : The treatment of naloxone yielded statistically higher significantly effective (69.4%) and effective rates ( 88. 9% ) when compared with control group ( both P 〈 0. 05 ). Conclusion: Featured by etiology-oriented characteristics, naloxone is effective for the treatment and prevention of apnea in preterm infants and should be regarded as worthwhile for clinical application.
作者 黄书炜
出处 《广州医学院学报》 2012年第6期81-82,共2页 Academic Journal of Guangzhou Medical College
关键词 纳洛酮 早产儿 呼吸暂停 naloxone preterm infant apnea
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