摘要
本文综述了重组人血清白蛋白在细菌 ,酵母 ,植物和动物等表达系统中表达的研究进展。用酵母表达系统 ,尤其是毕赤酵母 ,表达的重组白蛋白产量高且提取工艺简单 ,是其产业化最具有前途的表达系统。同时在转基因动物、植物中培养表达也具有诱人的前景。
It reviewed the progresses of the expression of recombinant human serum albumin which had been expressed in various hosts,such as bacteria,yeasts,transgenic animal cells,transgenic plant cells and so on.With high yields of rHSA and relative simple extraction technology,the yeast expression system,especially Pichia pastoris system,is the most prospect system in industrialization.Of course,the expression of rHSA in transgenic animal cells or in transgenic plant cells in also attractive.\;
出处
《生物工程进展》
CSCD
2000年第5期39-42,共4页
Progress in Biotechnology
基金
国家自然科学基金资助项目!(项目号 :2 99760 13 )