摘要
考察了奈替米星摇瓶发酵代谢特征，研究了磷酸盐和甲硫氨酸对菌丝生长和发酵单位的促进与提高作用。进而，以相同单位体积搅拌功率为基准放大，使１５ｔ发酵罐奈替木星发酵过程接近摇瓶水平。
Netilmicin n etabolic characteristics of shaking-flask fermentation were investigated. In 12L glass fermentor, it was showed that phosphate and methionine stimulated growth of mycelia and increased the production of antibiotic.On this basis, netilmicin fermentation had been scaled up successfully according to the standard of the same agitated power per unit volume from 12L fermentor to 5t fermentor.
出处
《微生物学通报》
CAS
CSCD
北大核心
2000年第5期356-359,共4页
Microbiology China
