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褪黑激素的抗衰老研究进展 被引量:10

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摘要 褪黑激素的抗衰老作用是目前的研究热点,它可以保护细胞核DNA,阻止细胞凋亡,激活或抑制某些基因的表达,并有直接和间接清除自由基的作用。本文综述了褪黑激素的抗衰老研究进展。
作者 何海蓉
出处 《国外医学(老年医学分册)》 2000年第5期226-228,239,共4页 Foreign Medical Sciences(Geriatrics)
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  • 11,Rossler R. Kloeden PE. Hoff A et al. Pitfalls and questions concerning the melationin anti-aging pill. In Proceedings of 2ndLocarno meeting on neuroendocrinoimmunity.199651
  • 22,Tan DX. Poeggler B. Reiter R et al. The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemicalsafrole in vivo. Cancer Lett.19937065~71
  • 33,Pomero MP. Osuna C. Garcia A et al. The pineal secretory product melatonin reduces hydrogen peroxide-induced DNA da-mage in U-937 cells. J Pineal Res.199926(4):227~235
  • 44,Vijayalaxmi. Reiter RJ. Meltz MZ et al. Melatonin possible me-chanisms involved in itsradioprotective effect. Mutat Res.1998404(1-2L187~189
  • 55,Ling X. Zhang LM. Lu SD et al. Over-expression of bcl-2 isassociated with protection of melatonin in neuronal injury fo-llowing a transient middle cerebral artery occusion inrats.ActaPharmacol Sin. 199920in press
  • 66,Ross AW. Barrett P. Mercer JG et al. Melatonin suppress theinduction of AP-1 trsnscription factor components in the parstuberalis of the pituitary. Mol Cell Endocrinol.1996123(1):71~80
  • 77,Gutteridge JMC. Hydroxyl radicals. iron. oxidative stress. andneurodegeneration. Ann NY Acad Sci.1994738201~213
  • 88,Reiter RJ. Melchiorri D. Seweerynek E et al. A review of theevidence supporting melatonin's role as an antioxidant. J Pin-el Res. 199518(1):1~11
  • 99,Tan DX. Chen LD. Poeggeler B et al. Melatonina potent en-dogenous hydroxyl radical scavenger. Endocrine J. 1993157~60
  • 1010,Xue-Jun Li. Jing Gu. Bai-Shen Pan et al. Effect of melato-nin on production of hydroxyl radical and lactata dehydroge-nase during hypoxia in rat cortical slice. Acta Pharmacol sin.199920(3):201~205

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