摘要
目的:应用光学相干断层成像术(optical coherence tomography,OCT)测量我国正常人黄斑视网膜神经上皮层(retinal neurosensory layer)和色素上皮层(retinal pigment epithelium,RPE)与脉络膜毛细血管层的厚度。方法:用OCT对60例(120眼)正常人进行经黄斑中央小凹水平和垂直扫描,扫描长度4mm,测量并计算黄斑中央小凹;距中央小凹鼻侧、颞侧、上方和下方175μm及750μm处视网膜神经上皮层和RPE与脉络膜毛细血管层厚度值的均数和标准差;对距中央小凹175μm及750μm各方位的视网膜神经上皮层和RPE与脉络膜毛细血管层厚度进行比较;将年龄与距中央小凹不同距离处视网膜神经上皮层厚度和RPE与脉络膜毛细血管层厚度进行相关分析。结果:黄斑中央小凹、距中央小凹175μm和750μm处视网膜神经上皮层平均厚度分别为:146.34±8.58μm,155.58±10.20μm和252.98±14.07μm;RPE与脉络膜毛细血管层平均厚度分别为:106.26±10.58μm,104.98±7.24μm和106.84±9.95μm。距中央小凹175μm处各方位视网膜神经上皮层厚度比较差异无显著性(P=0.430～0.855);RPE与脉络膜毛细血管层厚度比较差异也无显著性(P=0.331～0.889)。距中央小凹750μm处各方位视网膜神经上皮层厚度比较,除上方和下方之间差异无显著性(P=0.590)外,其余各方?
Objective: To measure the thickness of retinal neurosensory layer , retinal pigment
epithelium (RPE) and choriocapillaris in normal subjects by optical coherence
tomography (OCT).
Methods: Sixty normal subjects (120 eyes) were examined by OCT with 4mm scanning
length horizontally and vertically through foveola. The mean thickness of retinal
neurosensory layer, RPE and choriocapillaris thickness in foveola, 175 μm and 750μm
to foveola, were calculated and compared.
Results: The mean thickness of retinal neurosensory layer is 146. 34 ?8. 58 |xm in
foveola; 155. 58±10. 20 μm in 175 μm to foveola and 252. 98±14. 07 μm in 750 μm
to foveola. The mean thickness of RPE and choriocapillaris is 106. 26±10. 58μm in foveola;104,98±7.24μm in 175μm to foveola and 106.84±9.95μm in 750 μm to
foveola. The results show that there are no significant in mean thickness of retinal
neurosensory layer in 175μm to foveola in statstics, but there are differenees in 750μm to foveola between nasal and temporal or superior. inferior and nasal, temporal.The
differences in mean RPe and chorioeapillaris thickness of all sites are not significant.
Correlative analysis showed that there is no correlation between retinal neurosensory
layer. PRE and choriocapillaris thickness and age
Conclusion: OCT can accurately measure the hickness of retina in normal eyes and
provide a subjective and Quantitative method to diagnose macular diseases. Eye Science 2000:16:87-90
出处
《眼科学报》
2000年第2期87-90,共4页
Eye Science
关键词
光学相干断层成像
视网膜厚度
黄斑
optical coherence tomography(OCT),retinal thickness,macula lutea
