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急性白血病患儿MTHFR基因G1793A多态性的相关研究 被引量：1

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作者 郑苗苗 岳丽杰 杨春兰 谢偲 丁慧
机构地区 合肥医学院深圳市儿童医院儿科研究所
出处 《中华实用儿科临床杂志》 CAS CSCD 北大核心 2013年第3期191-194,共4页 Chinese Journal of Applied Clinical Pediatrics
基金 国家自然科学基金（30471830） 深圳市科技计划项目（200802065）
关键词 MTHFR基因 白血病患儿 多态性 急性
分类号 R733 [医药卫生—肿瘤]
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参考文献24

  • 1Safarinejad MR,Shafiei N,Safarinejad SR. Gene C677T,A1298C and G1793A polymorphisms:association with risk for clear cell renal cell carcinoma and tumour behaviour in men[J].Clinical Oncology,2012,(04):269-281.
  • 2Tong N,Sheng X,Wang M. Methylenetetrahydrofolate reductase gene polymorphisms and acute lymphoblastic leukemia risk:a meta-analysis based on 28 case-control studies[J].Leukemia and Lymphoma,2011,(10):1949-1960.
  • 3Damnjanovic T,Milicevic R,Novkovic T. Association between the methylenetetrahydrofolate reductase polymorphisms and risk of acute lymphoblastic leukemia in Serbian children[J].Pediatric Hematology and Oncology,2010,(04):e148-e150.
  • 4Jiang Y,Zhao J,Jiang T. Genetic polymorphism of methylenetetrahydrofolate reductase G1793A,hyperhomocysteinemia,and folate deficiency correlate with ulcerative colitis in central China[J].Journal of Gastroenterology and Hepatology,2010,(06):1157-1161.
  • 5Haghighi MM,Mohebbi SR,Sadeghi RN. Association between the 1793G 》 A MTHFR polymorphism and sporadic colorectal cancer in Iran[J].Asian Pacific Journal of Cancer Prevention,2008,(04):659-662.
  • 6Safarinejad MR,Shafiei N,Safarinejad S. Genetic susceptibility of methylenetetrahydrofolate reductase (MTHFR) gene C677T,A1298C,and G1793A polymorphisms with risk for bladder transitional cell carcinoma in men[J].Medical Oncology,2011,(01):398-412.
  • 7Safarinejad MR,Shafiei N,Safarinejad S. Relationship between three polymorphisms of methylenetetrahydrofolate reductase(MTHFR C677T,A1298 C,and G1793A)gene and risk of prostate cancer:a case-control study[J].Prostate,2010,(15):1645-1657.
  • 8顾龙君.儿童急性淋巴细胞白血病诊疗建议(第三次修订草案)[J].中华儿科杂志,2006,44(5):392-395. 被引量：485
  • 9顾龙君.儿童急性髓细胞白血病诊疗建议[J].中华儿科杂志,2006,44(11):877-878. 被引量：168
  • 10Rady PL,Szucs S,Grady J. Genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) in ethnic populations in Texas;a report of a novel MTHFR polymorphic site,G1793A[J].American Journal of Medical Genetics,2002,(02):162-168.

二级参考文献28

  • 1杨丽华,卢新天,卢炜,华瑛,赵卫红,卢薇薇.淋巴系恶性肿瘤患儿大剂量氨甲蝶呤剂量个体化的临床研究[J].临床儿科杂志,2006,24(2):104-106. 被引量：6
  • 2顾龙君.儿童急性淋巴细胞白血病诊疗建议(第三次修订草案)[J].中华儿科杂志,2006,44(5):392-395. 被引量：485
  • 3杨旭燕,许东航.亚甲基四氢叶酸还原酶基因多态性对甲氨蝶呤不良反应的影响[J].中国药学杂志,2007,42(1):69-72. 被引量：12
  • 4Pui CH.Recent advances in acute lymphoblastic leukemia[J].Oncolo-gy(Williston Park),2011,25(4):346-347.
  • 5余晶 杨丽华 兰和魁 等.MTHFR基因多态性与儿童急淋白血病易感性关系研究.中国实用儿科杂志,2010,25(1):21-24.
  • 6Cwiklińska M,Balwierz W,Stanuch H.Clinical tolerance of high-dosemethotrexate used in consolidation therapy in children with acute lym-phoblastic leukemia[J].Przegl Lek,2010,67(6):355-360.
  • 7Schmiegelow K.Advances in individual prediction of methotrexate toxic-ity:A review[J].Br Haematol,2009,146(5):489-503.
  • 8D'angelo V,Ramaglia M,Iannotta A,et al.Methotrexate toxicity andefficacy during the consolidation phase in paediatric acute lymphoblasticleukaemia and MTHFR polymorphisms as pharmacogenetic determinants[J].Cancer Chemother Pharmacol,2011,68(5):1339-1346.
  • 9Imanishi H,Okamura N,Yagi M,et al.Genetic polymorphisms associatedwith adverse events and elimination of methotrexate in childhood acutelymphoblastic leukemia and malignant lymphoma[J].J Hum Genet,2007,52(2):166-171.
  • 10Lopez-Lopez E,Ballesteros J,Garcia-Orad A.MTHFR 677TT geno-type and toxicity of methotrexate:Controversial results[J].Cancer Che-mother Pharmacol,2011,68(5):1369-1370.

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中华实用儿科临床杂志
2013年 第3期

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