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尿激酶受体与肿瘤 被引量:5

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摘要 尿激酶受体 (u PAR ,CD87)是纤溶系统中的一个多功能受体 ,介导纤溶酶原的活化、信号传递及细胞的粘附等。它在肿瘤的生长、浸润和转移过程中也起着重要的作用 ,并和肿瘤的恶性程度相关。检测肿瘤细胞表面u PAR或血浆中可溶性u PAR(su PAR)的水平 ,有助于了解肿瘤病人病情及预后。阻止尿激酶 (u PA)与其受体的结合抑或调节肿瘤细胞表面u PAR的表达 ,可以抑制肿瘤的浸润和转移 ,达到治疗肿瘤的目的。
出处 《国外医学(肿瘤学分册)》 北大核心 2000年第5期289-291,共3页 Foreign Medical Sciences (Cancer Section)
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同被引文献66

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