摘要
目的:探讨头颈部炎性肌纤维母细胞瘤的临床病理特点、治疗方法及疗效。方法:回顾性分析6例经病理确诊的头颈部炎性肌纤维母细胞瘤患者的临床资料。结果:6例患者均行手术治疗,随访6个月～7年。至末次随访,2例死亡,2例带瘤生存,2例无瘤生存。结论:炎性肌纤维母细胞瘤最多发生于肺,发生于头颈部者极为罕见。诊断主要依靠病理及免疫组织化学检测。治疗以手术扩大切除为主,术后复发率较高,需长期随访。术后放化疗疗效差。
Objective：To investigate the clinicopathological features , therapeutic methods and therapeutic ef- ficacy of imflammatory myofibroblastic tumor （IMT） in head and neck region. Method.. Clinical data of 6 cases which were diagnosed by pathology and immmunohistochemistry from January 2004 to June 2011 were retrospec- tively analyzed. All cases were confirmed by pathology and immmunohistochemistry. Result.. All cases were opera- ted. All the patients were followed up for a period of 6 months to 7 years after operation. Two patients died of tumor until the last follow-up,while 2 cases lived with no evidence of disease. Conclusion：IMT is a very rare tumor in head and neck region,which often occurs in lung. The diagonosis of IMT is based on pathology and immunohis- tochemistry. Extended local excision with tumor-free margin is the treatment of choice. Chemotherapy and radio- therapy may not be helpful to prevent recurrence after operation. Due to high recurrence rate, long-term follow up is necessary after operation.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2013年第6期325-328,共4页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
头颈部肿瘤
炎性肌纤维母细胞瘤
head and neck neoplasms
imflammatory myofibroblastic tumor
