摘要
目的探讨治疗抑郁症有效方法并观察抑郁症综合治疗的效果。方法筛选抑郁症患者100例,作为被试并分为观察组和对照组各50例。两组患者均从入组开始即给予正规抗抑郁药物治疗,并根据病情及对药物治疗的反应情况调整药物种类和剂量,连续观察7个月。在此基础上观察组采用综合治疗方法,即药物治疗+运动疗法+"叙事式"愉悦因子输入疗法。疗效采用汉密尔顿抑郁量表(HAMD)分别于治疗前和治疗后1个月、3个月、5个月、7个月时进行评定。以患者治疗前后减分率为依据制定疗效标准,总有效率包括治愈、显著好转及好转。结果两组患者治疗前HAMD评分无显著性差异;观察组在治疗后1个月、3个月、5个月、7个月不同观察时段HAMD评分均明显低于对照组(t=19.248,17.585,10.210,18.901;P<0.01),具有非常显著性差异;整体疗效也显示观察组总有效率100%,对照组78%,差异显著(P<0.01)。结论采用药物口服、运动和愉悦因子输入之综合疗法对社区不同类型抑郁症治疗,具有良好的协同作用,明显优于单一药物治疗。
Objective To explore a more effective method for the treatment of depression,and observe the effect of comprehen- sive therapy on depression. Methods A total of 100 patients with depression were screened and divided into the observation group and the control group（50 patients）. Patients were enrolled by giving formal antidepressant drug treatment,and drug type and dose adjusted according to the disease and response to drug therapy,continuous observation of 7 months. The observation group took comprehensive therapy on this basis,that the drug therapy ＋ exercise therapy ＋ pleasure factor input therapy. Using the HRSD to assess efficacy before treatment and 1 month, 3 months, 5 months, 7 months. And using the difference value of score before and af- ter treatment to develop the curative standard：efficient cure,significantly improved and improved. Results HAMD score of pa- tients in the two groups was no significant difference before treatment （t = 0. 861,P〈0.05）;The HAMD scores of the observation group were significantly lower than those of the control group in 1 month, 3 months, 5 months,7 months after treatment （t = 19. 248, 17. 585,10. 210,18. 901;both P〈0.01）;The total effective rate of observation group （100%）was significantly higher than that of control group（78%）（P〈0.01）. Conclusion The drug therapy ＋ exercise therapy ＋ pleasure factor input therapy has good synergies for different types of depression,and significantly better than a single drug treatment.
出处
《中国健康心理学杂志》
2013年第3期341-343,共3页
China Journal of Health Psychology
