摘要
目的探讨老年2型糖尿病患者的认知障碍危险因素,为防治糖尿病患者认知功能减退提供参考依据。方法选取老年糖尿病患者299例,糖尿病伴认知障碍患者147例为观察组,单纯糖尿病患者152例为对照组。对2组患者相关指标进行对比分析。结果2组患者在C肽水平、糖尿病病程、高血压病史、最小颈动脉阻力指数(RI)、最大颈动脉内膜中层厚度(IMT)方面比较有显著性差异(P均<0.05)。结论 C肽水平、糖尿病病程、高血压病史、RI以及IMT可能是老年2型糖尿病患者出现认知障碍的危险因素,要加强对低水平C肽、动脉硬化以及高血压的检测和干预,通过认知功能障碍量表不定期对老年2型糖尿病患者进行筛查。
Objective It is to approach the risk factors of cognitive impairment in elderly patients with type 2 diabetes mullites （rF2DM） , and provide the reference basis for prevention and cure of T2DM with cognitive impairment. Methods 299 elderly patients with T2DM diabetes were selected and divided into 2 groups, 147 patients with diabetes and cognitive impairment in observation group and 152 cases with only diabetes in control group. Relevant indicators such as C peptide levels, dtlration of diabetes, minimum carotid resistive index （RI）, and maximum carotid intima-media thickness （IMT） of the two groups were compared and analyzed. Results There were significant difference in C peptide levels, duration of diabetes, hypertension, minimum RI and maximum IMT of the common carotid artery between the two groups （P 〈 0.05）. Conclusion C peptide levels, duration of diabetes, hypertension, RI and IMT may be the risk factor of elderly T2I）M patients cognitive impairment, ought to strengthen the low levels of C peptide, atherosclerosis, and hypertension detection and intervention by the cognitive dysfunction Scale occasional screening of elderly patients with type 2 diabetes.
出处
《现代中西医结合杂志》
CAS
2013年第9期925-927,共3页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
2型糖尿病
认知障碍
危险因素
type 2 diabetes mullites
mild cognitive impairment
risk factors
