摘要
硒蛋白P(Selenoprotein P,Sepp1)是一种由2个结构域构成的分泌性糖蛋白。血浆中多数Sepp1均源于肝脏,肝脏合成的Sepp1能影响整个机体的硒含量,因此Sepp1在维持机体内硒的动态平衡和分布上起着关键作用。另外,血浆中的Sepp1能够调控微量元素硒缺乏,也是检测硒含量的指标之一。本文就Sepp1结构及功能的研究进展作一综述。
Selenoprotein P （Seppl） is a secretory glycoprotein consisting of two domains. Most of Seppl in plasma is derived from liver, which affects the selenium content in the whole organism and plays an important role in maintaining the dynamic equilibrium and distribution of Seppl. In addition, plasma Seppl concentration may regulate, which is also an index of selenium nutritional status. This paper reviews the progress in study on structure and function of Seppl.
出处
《中国生物制品学杂志》
CAS
CSCD
2013年第3期437-440,共4页
Chinese Journal of Biologicals
关键词
硒蛋白P
结构
功能
Selenoprotein P
Structure
Function
