摘要
目的 观察葛根素注射液治疗糖尿病周围神经病变 (DPN)的疗效。方法 采用葛根素注射液治疗 DPN 6 6例 ,同时与甲钴胺治疗的 2 2例作对照 ,观察葛根素注射液对 DPN患者肌电图、空腹血糖、糖化血红蛋白、血液流变学及红细胞山梨醇的影响。结果 治疗组显效率为 5 1.5 1% ,对照组为 2 2 .72 % (P<0 .0 1)。治疗组总有效率为 89.39% ,对照组为 5 8.10 % (P<0 .0 5 ) ,治疗组在治疗后 ,空腹血糖略有下降 (P>0 .0 5 ) ,糖化血红蛋白有显著下降 (P<0 .0 1) ,血流变学有明显改善。红细胞山梨醇有明显下降 (P<0 .0 1)。结论 葛根素治疗 DPN有较好疗效。
Objective To investigate the effects of puerar in injection on the diabetic preipheral neuropathy (DPN).Methods Comparing sixty-six cases in puerar treat group with twenty-two cases in mecobalamin control group.And observing the effects of puerar in injection on the electromyo graphy,FBG,HbAlc,hemorheology and erythrocyte polyol.Results Marked effective rate:51.51% (treat group);22.72% (control group) ( P <0 01).Effective rate:89.39% (treat group ); 58.10% (control group) ( P <0 05).In treat group after treatment,FBG fell slightly without any meaning in statistics ( P >0 05);HbA1c decreased markedly ( P <0 01);hemorheology improved evidently;erythrocyte polyol decreased conspicuously ( P <0 01).Conclusion Puerar in injection has a good effect in DPN remedy.
出处
《中国糖尿病杂志》
CAS
CSCD
2000年第5期269-271,共3页
Chinese Journal of Diabetes
关键词
糖尿病
周围神经病变
蛋白非酶糖基化
Diabetic peripheral neuropathy (DPN) Protein nonenzymatic glycation Aldose reductase inhibitor
