摘要
目的探讨静脉滴注单硝酸异山梨酯治疗冠心病心绞痛的临床疗效及不良反应。方法以我院76例冠心病性心绞痛患者为研究对象,将其随机分为观察组和对照组,分别采用静脉滴注单硝酸异山梨酯与静脉滴注硝酸甘油进行对比治疗,观察疗效。结果观察组总有效率为94.7%,对照组总有效率为78.9%,两组疗效比较,差异有统计学意义(P<0.05)。结论单硝酸异山梨酯静脉滴注治疗冠心病心绞痛疗效显著,吸收好、生物利用度高,较硝酸甘油作用时间长而不良反应少,值得在临床推广使用。
Objective To investigate the clinical efficacy and adverse effects of intravenous infusion isosorbide monon- itrate in treatment of angina pectoris. Methods In our hospital 76 cases of angina pectoris of coronary heart disease patients as the research object, it will be randomly divided into observation group and control group, respectively, by intravenous injection of isosorbide mononitrate and intravenous infusion of nitroglycerin compared treatment, curative effect observation. Results The total effective rate in the observation group was 94. 7%, the total efficiency of control group was 78. 9%, compared with two groups of curative effect, the difference was statistically significant （P 〈 0. 05）. Conclusion The efficacy of intravenous infusion isosorbide mononitrate in treatment of angina pectoris was good with better absorption, high bioavailability, lasting effect and fewer adverse reactions, which was worthy of clinical use.
出处
《实用心脑肺血管病杂志》
2013年第3期67-67,69,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
单硝酸异山梨酯
冠心病
心绞痛
治疗结果
Isosorbide mononitrate
Conronory disease
Angina pectoris
Treatment outcome
