摘要
目的 了解镓盐对骨质疏松症的治疗作用进行了以大鼠对象的实验研究。方法 实验分两步进行，首先去除成年大鼠卵巢，复制骨质疏松模型；然后应用镓盐进行治疗。采用骨强度测定和骨病理形态学方法观察骨结构的改变情况。结果 ①骨质疏松组与对照组相比各指标均下降，差异具有统计学意义；②镓治疗组与骨质疏松组相比，骨吸收的病理变化减轻，差异具有统计学意义，骨强度亦有提高的趋势。结论 镓盐对骨质疏松症有治疗或减缓其进程的作用。
Objective\ To acquire the effect of gallium salt on pr e venting and treating osteoporosis.Methods\ The experiment was compos ed of two steps:①Duplicating an animal model of osteoporosis;②Treating the rat s with gallium salt.Results\ ①All the experimental parameters of os teoporosis decreased and had significant difference compared to those of the con trols;②The pathologic bone resorption changes in therapeutic group are alleviat ed and have significant difference in comparison to control group.The bone inten s ity also appeared an improving trend.Conclusion\ Gallium salt has th erapeutic effect on osteoporosis or is able to retard the progress of this disea se.
出处
《西安医科大学学报》
CAS
CSCD
2000年第5期415-416,419,共3页
Journal of Xi'an Medical University(Chinese)
关键词
骨质疏松症
镓盐
骨强度
osteoporosis
gallium salt
bone intensity
