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猪囊尾蚴病免疫治疗研究 被引量:14

STUDIES ON THE IMMUNOTHERAPY OF CYSTICERCOSIS
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摘要 本研究进行了两次攻虫—免疫实验 ,第一次实验应用仔猪 2 0头 ,于攻虫前两周分别用 1,0 0 0万和 2 ,0 0 0万猪囊尾蚴细胞加代谢产物疫苗进行免疫 ,然后攻虫 ,攻虫量为 6 0 0 0枚 /头人有钩绦虫六钩蚴虫卵 ;第二次实验应用仔猪 10头 ,先攻虫卵380 0 0枚 /头 38天后再用 1,0 0 0万猪囊尾蚴细胞加代谢产物疫苗免疫 ,然后剖检猪体内虫体。结果 第一次实验的两个组 10 0 %的猪 ,体内囊尾蚴虫体发生了钙化 ,第二次实验有 6 6 .7%的猪 ,体内囊尾蚴发生钙化现象 ,两次实验猪的平均钙化率为 87.5 % 。 The research on the immunotherapy of Cysticercosis includes two experiments.20 heads of piglets were used in the first experiment.Two weeks before attacking-larvae,we immunized the experiment piglets with ten or twenty million cell vaccine of Cysticercus Cellulosae cell line's cells and its metabolite respectively.Than attacked with larvae.the volume is 6.000 ova of Taenia Solium Oncosphere per heads.In another experiment 10 heads of piglets were used.After 38 days of attacking-larvae of Taenia Solium Oncosphere Ova,we immunized the experiment piglets with ten millon cell vaccine of Cysticercus Cellulosae cell line's cells and its metabolite.After a certain time,we dissected all of the experiment piglets and examined the state of infected Cysticercus Cellulosae in the body.And the results are as follows:in the first experiment, 100 percent of the two groups of piglets calcifid in that of the Cysticercuses;and in the second experiment.We found that 66.7 percent of the piglets with calcified Cysticercuses.The average calcification rate of the twice exper iments is 87.5 percent.The inactivity cell vaccine of Cysticercus Cellulosae is a good agent of immunity treatment. \ \
出处 《中国人兽共患病杂志》 CSCD 北大核心 2000年第6期33-36,共4页 Chinese Journal of Zoonoses
基金 国家"九五"重点科技攻关项目
关键词 猪囊尾蚴病 猪囊尾蚴细胞疫苗 免疫治疗 Cysticercosis The cell vaccine of Cysticercus Cellulosae Immunotherapy
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