摘要
目的分析血清单胺氧化酶(MAO)、前清蛋白(PA)及胆碱酯酶(CHE)在肝硬化早期诊断中的应用价值。方法 2010年1月至2011年11月,分别检测97例慢性肝炎患者和83例肝硬化患者(其中代偿期组46例、失代偿期37例)血清中MAO、PA及CHE水平变化。结果肝硬化组血清MAO明显高于健康对照组(P<0.05),PA及CHE明显低于健康对照组的(P<0.05),慢性肝炎患者组血清MAO、PA及CHE与健康对照组相比差异无统计学意义(P>0.05)。失代偿期组血清MAO均明显高于代偿期组(P<0.05),PA及CHE明显低于代偿期组的(P<0.05)。结论血清MAO水平在肝硬化患者中明显升高、PA和CHE水平在肝硬化患者中明显降低,并且其水平与肝硬化的病情发展密切相关,可以作为肝硬化早期发现的指标,用于临床检测。
Objective To analyze the application value of monoamine oxidase（MAO）, pre-albumin（PA） and cholinesterase（CHE） in the early stage diagnosis of liver cirrhosis. Methods From January 2010 to November 2011, the changges of serum MAO,PA and CHE level in 97 patients with chronic hepatitis and 83 patients with liver cir- rhosis（including 46 cases in compensated group,and 37 cases in decompensated group） were examined. Results The serum MAO of liver cirrhosis group was significantly higher than that of control group（P〈0.05） ,PA and CHE were significantly lower than those in control group （P 〈0.05 ）. In patients with chronic hepatitis, serum MAO, PA and CHE showed no significant difference compared with the control group（P〈0.05）. The serum MAO of the decom- pensated group were significantly higher than that in the decompensated group（P〈0.05）, while PA and CHE were significantly lower than those of compensated group（P〈0.05）. Conclusion The serum MAO level in patients with liver cirrhosis is significantly increased,while PA and CHE levels in patients with liver cirrhosis are significantly re- duced. These indicators are closely related to the disease development of cirrhosis, and can be used as clinical detection indicators for the early diagnosis of liver cirrhosis.
出处
《检验医学与临床》
CAS
2013年第4期433-434,共2页
Laboratory Medicine and Clinic
关键词
单胺氧化酶
前清蛋白
胆碱酯酶
肝硬化
monoamine oxidase
pre-albumin
cholinesterase
liver cirrhosis
