摘要
目的分析乙型肝炎病毒(HBV)感染者的血清单胺氧化酶(MAO)活性,探讨MAO活性分析在HBV感染者的临床应用价值。方法回顾分析了284例HBV感染者及123例正常对照者的血清MAO活性水平。结果与正常对照组比较,A组(ALT升高,大三阳者)、B组(ALT升高,小三阳、HBV-DNA阳性者)、D组(ALT正常,大三阳)MAO均呈明显升高(P<0.01);C组(ALT升高,小三阳、HBV-DNA阴性者)、E组(ALT正常,小三阳、HBV-DNA阳性者)、F组(ALT正常,小三阳、HBV-DNA阴性者)MAO水平无显著性变化(P>0.05)。结论对HBV感染者进行血清MAO活性分析,有助于了解肝细胞损害情况,预测肝纤维化的发生,对病情判断有重要意义。
Objective To analyze the activity of Monoamine Oxidase（MAO） in the patients with hepatitis B virus（HBV）,and study the value of the analysis of MAO activity in the patients with HBV.Methods The MAO activity levels of 284 patients with HBV and 123 normal controls were reviewed.Results Compared with in the normal control group,the MAO activity levels were all significantly higher in Group A（the patients with increased ALT,HbsAg（＋）,HBeAg（＋） and anti-HBc（＋））,Group B（the patients with increased ALT,HBsAg（＋）,anti-HBe（＋） and anti-HBc（＋） and HBV-DNA（＋））,Group D（the patients with normal ALT,HBsAg（＋）,HBeAg（＋） and anti-HBc（＋））（P0.01）;the MAO activity levels were all not significantly different in Group C（the patients with increased ALT,HBsAg（＋）,anti-HBe（＋） and anti-HBc（＋） and HBV-DNA（-））,Group E（the patients with normal ALT,HBsAg（＋）,anti-HBe（＋） and anti-HBc（＋） and HBV-DNA（＋））,Group F（the patients with normal ALT,HBsAg（＋）,anti-HBe（＋） and anti-HBc（＋） and HBV-DNA（-））（P〉0.05）.Conclusion analyzing the MAO activity in the Patients with HBV,is helpful to learn information about hepatocellular damage and predict the occurrence of liver fibrosis,so the analysis of MAO activity is very important for the judgment of pathogenetic condition in the patients with HBV.
出处
《中国实验诊断学》
北大核心
2009年第10期1391-1392,共2页
Chinese Journal of Laboratory Diagnosis
