期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

二甲双胍对乳腺癌的防治研究进展 被引量：5

原文传递
导出
摘要 研究显示二甲双胍可降低糖尿病患者乳腺癌的发生率及提高其生存率，具体机制包括胰岛素依赖型效应、胰岛素非依赖型效应、激活免疫及杀灭肿瘤干细胞等，大规模临床试验正在开展中，以进一步确定二甲双胍在乳腺癌预防及治疗中的作用。然而，距离将其真正应用到临床还有很多疑问亟须解决。
作者 魏金丽 邵稳喜 章佳新
机构地区 江苏省苏北人民医院甲乳外科
出处 《中华全科医师杂志》 2013年第2期116-118,共3页 Chinese Journal of General Practitioners
关键词 二甲双胍 乳腺肿瘤
分类号 R737.9 [医药卫生—肿瘤]
  • 相关文献

参考文献38

  • 1Wolf I,Sadetzki S,Catane R. Diabetes mellitus and breast cancer[J].Lancet Oncology,2005,(2):103-111.
  • 2Dilman VM. Age-associated elevation of hypothalamic,threshold to feedback control,and its role in development,ageing and disease[J].Lancet,1971.1211-1219.
  • 3Goodwin PJ,Stambolic V,Lemieux J. Evaluation of metformin in early breast cancer:a modification of the traditional paradigm for clinical testing of anti-cancer agents[J].Breast Cancer Research and Treatment,2011.215-220.
  • 4Renehan AG,Frystyk J,Flyvbjerg A. Obesity and cancer risk:the role of the insulin-IGF axis[J].Trends in Endocrinology and Metabolism,2006.328-336.
  • 5Decensi A,Puntoni M,Goodwin P. Metformin and cancer risk in diabetic patients:a systematic review and meta-analysis[J].Cancer Prev Res,2010.1451-1461.
  • 6Hadden DR. Goat's rue-French lilac-Italian fitch-Spanish sainfoin:gallega officinalis and metformin:the Edinburgh connection[J].Journal of Royal College of Physicians of Edinburgh,2005.258-260.
  • 7Dilman VM,Berstein LM,Ostroumova MN. Metabolic immunodepression and metabolic immunotherapy:an attempt of improvement in immunologic response in breast cancer patients by correction of metabolic disturbances[J].Oncology(Basel),1982.9-13.
  • 8Schott S,Bierhaus A,Schuetz F. The therapeutic effects of metformin in breast cancer:involvement of the immune system[J].Cancer Immunology Immunotherapy,2011.1221-1225.
  • 9Gonzalez-Angulo AM,Meric-Bernstan F. Metformin:a therapeutic opportunity in breast cancer[J].Clinical Cancer Research,2010.1695-1700.
  • 10Liu B,Fan Z,Edgerton SM. Metformin induces unique biological and molecular responses in triple negative breast cancer cells[J].Cell Cycle,2009,(13):2031-2040.

同被引文献60

  • 1中国抗癌协会乳腺癌专业委员会.中国抗癌协会乳腺癌诊治指南与规范(2011版)[J].中国癌症杂志,2011,21(5):367-417. 被引量：281
  • 2Frei E. Clinical cancer research: an embattled species[J]. Cancer, 1982 50(10): 1 979 - 1 992.
  • 3Tokunaga E,Oki E, Nishida K,et development and current status[J] 11(3): 199-208. al. Trastuzumab and breast cancer: Journal of Clinical Oncology, 2006,.
  • 4Jiralerspong S, Palla SL, Giordano SH, et al. Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer[J]. Journal of Clinical Oncology,2009,27(10): 3 297 - 3 302.
  • 5Googwin PJ, Stambolic V, Lemieux J, et al. Evaluation of metfomin in early breast eanccr: a modification of the traditional paradigm for clinical testing of anti - cancer agents [J]. Breast Cancer Res Treat,2011,126 ( 1 ) : 215 - 220.
  • 6Wilson JM, Jungner YG. Principles and practice of mass screening for disease [ J]. Bol Oficina Sanit Panam, 1968, 65(4) :281-393.
  • 7Pace LE, Keating NL A systematic assessment of benefits and risks to guide breast cancer screening decisions [ J ]. JAMA,2014, 311 ( 13 ) : 1327-1335. doi: 10. 1001/jama. 2014. 1398.
  • 8Kasters JP, Gctzsche PC. Regular self-examination or clinical examination for early detection of breast cancer [ J ]. Cochrane Database Syst Rev, 2003, (2) : CD003373.
  • 9US Preventive Services Task Force. Screening for breast cancer: U.S. preventive services task force recommendation statement [ J ]. Ann Intern Med, 2009,151 ( 10 ) : 716-726. doi: 10. 7326/ 0003-4819-151-10-200911170-00008.
  • 10Canadian Task Force on Preventive Health Care, Tonelli M, Connor Gorber S, et al. Recommendations on screening for breast cancer in average-risk women aged 40-74 years [ J]. CAM J, 2011, 183 ( 17 ) : 1991-2001. doi : 10. 1503/cmaj. 110334.

引证文献5

二级引证文献5

中华全科医师杂志
2013年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部