摘要
目的:分析药学干预前后医院门诊处方抗菌药物的使用情况,对处方完整性和用药合理性进行分析、评价,为临床合理用药提供参考。方法:根据《处方管理办法》、《抗菌药物临床应用指导原则》、医院制定的《处方评价制度》和有关文献,构建抗菌药物计算机管理系统,组建抗菌药物合理使用考核组,综合制定干预抗菌药物应用的措施。以随机抽样法抽取2009年9、10月(干预前)及2010年9、10月(干预后)处方各5 000张,制作电子表格对应用抗菌药物的处方进行统计、分析。结果:2009年9、10月5 000张处方中,应用抗菌药物处方1 956张(占39%),2种及2种以上抗菌药物联合应用处方23张(占1.18%),不合理处方98张(占抗菌药物处方的5.01%);2010年9、10月5 000张处方中应用抗菌药物处方813张(占16.26%),2种及2种以上抗菌药物联合应用处方7张(占0.86%),不合理处方38张(占抗菌药物处方的4.67%)。通过采取处方点评干预措施,不合理用药明显减少,处方质量显著提高。结论:采取综合干预措施可降低抗菌药物使用率,使其应用更趋合理。
OBJECTIVE：To analyze the outpatient antibiotic use before and after pharmaceutical intervention and evaluate the completeness of the prescriptions and rationality of antibiotic use so as to provide reference for clinical rational drug use.METHODS：According to ＂Prescription Management Method＂ and the ＂Guiding Principles for Clinical Application of Antibacterials＂ and ＂Prescription Evaluation System＂,computer management system on antibacterials was constructed and a team on examining rational use of antibiotics was organized and measures was taken aimed at rational use of antibiotics.5 000 outpatient prescriptions from September to October in 2009（before intervention） and another 5 000 from September to October in 2010（after intervention） were randomly selected for analysis of the use of antibiotics by making spreadsheets.RESULTS：Of the 5 000 prescriptions sampled during Sept.-Oct.2009,antibiotics were used in 1 956（39%）,and concurrent use of at least two antibiotics was noted in 23（1.18%） and irrational drug use in 98（5.01%）;of the 5000 prescriptions sampled during Sept.-Oct.2010,antibiotics were used in 813（16.26%）,and concurrent use of at least two antibiotics in 7（0.86%） and irrational drug use in 38（4.67%）.The intervention of comment on prescriptions,the proportion of irrational use of antibiotics was significantly reduced while the quality of the prescriptions of antibiotics was significantly improved.CONCLUSION：The intervention measures can reduce the rate of antibiotic use and make the antibiotics use more rational.
出处
《中国医院用药评价与分析》
2012年第11期1052-1054,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
门诊处方
抗菌药物
处方分析
合理用药
Outpatient prescription
Antibacterial
Analysis of prescription
Rational use of drug
