摘要
用柔嫩艾美耳球虫卵囊活苗对京白雏鸡进行一次免疫、二次免疫及涓滴免疫试验,对免疫后、雏鸡腔上囊、脾脏、胸腺及盲肠扁桃体等组织器官的免疫应答作了较为详细的观察。免疫后上述组织器官淋巴细胞明显增多,形成大量淋巴滤泡;通过对免疫组和对照组雏鸡上述免疫组织器官的对照检查,表明三种免疫方法免疫后腔上囊、脾脏、胸腺及盲肠扁桃体均呈现不同程度的增生,其中以涓滴免疫和二次免疫比较明显。试验结果提示,一次免疫、二次免疫及涓滴免疫均可刺激机体免疫组织器官淋巴细胞大量增生,产生有效的免疫应答反应,对强毒攻击表现有效的抵抗力。
The result obtained from experiment with single dose,two doses of oocysts and trickle immunizations of Eimeria tenella oocysts in chickens were reported.Histological morphology in the bursa Fabricia,spleen,thymus and ton sil of caeca in the immunized chickens inoculated with three kinds of metho- ds was observed.A large amount of lymphocytes accumlated and formed lymp- hatic follicles in each organ above.The results obtained from observing histo- logical changes of caecal tonsil,thymus,spleen and bursa Fabricia showed that four kinds of organs of the immunized group had different degree of hyperpla- sia.The organs of the chickens with two doses of oocysts and continuous low level oocysts inoculations appeared significant histological changes.The results demomstrated that chickens with one single dose oocysts,two doses of oocysts, and trickle inoculations were induced effective immune response and provided with substantial resistance to the subsequent heavy challengc.
关键词
形态学
免疫
鸡
器官
艾美耳球虫
morphology
immunological response
immune organ
one single dose immunization
two doses immunization
trickle immunization
Eimeria tenella
Beijing white leghorn chicken
