摘要
目的研究甘草不同柱分的体外抗肿瘤活性。方法采用MTT法检测甘草不同柱分对人喉癌细胞(Hep-2)增殖的抑制作用。结果甘草不同柱分对Hep-2细胞有明显抑制作用,随着浓度的升高而增强,且呈浓度一效应关系。HPD722-70柱分间(F=32.906,P=0.001)、浓度间(F=2.255,P=0.042)与D101-80柱分的浓度间(F=19.703,P=0.001)抑制率的差异有统计学意义(P<0.05)。结论甘草不同柱分在体外具有显著的抗肿瘤活性。
Objective The effect of the extractions of glycyrrhizae on anti-tumor activity in vitro was studied. Methods The inhibitory action on tumor cell Hep-2 with MTY was determined. Results The inhibitory action was obvious, reinforced as the concentrations increased, and showed a concentration-effect relation. There was statistical difference of inhibition ratio among HPD722-70 serial extractions （ F = 32. 906, P = 0. 001 ） and also among different concentrations of HPD722-70 （F=2.255,P=0.042）and D101-80 （F= 19. 703,P =0.001）series extractions（P 〈0. 05）. Conclusions The anti-tumor activity of glycyrrhizae extractions in vitro was obvious.
出处
《公共卫生与预防医学》
2013年第1期6-9,共4页
Journal of Public Health and Preventive Medicine
基金
广州市科学技术局(编号:44541075)
关键词
甘草
体外
抗肿瘤
Radix Glycyrrhizae
In vitro
Anti-tumor activity
