摘要
目的分析类风湿关节炎(RA)医院感染的临床特点,正确做好预防与控制感染的措施。方法回顾性调查2006年9月-2011年11月医院RA住院患者,将其信息进行详细登记,汇总分析所得数据。结果 1113例类风湿关节炎患者中,发生医院感染226例、238例次,感染率为20.29%、例次感染率21.38%;泌尿道和下呼吸道是主要的感染部位,占80.67%;238例次感染部位均做病原学检测,234例培养阳性,共检出病原体298株,其中革兰阴性菌134株、革兰阳性菌82株、真菌13株、支原体属69株,分别占44.97%、27.52%、4.36%、23.15%,不同感染部位病原菌存在差异。结论类风湿关节炎医院感染的发病率较其他疾病合并医院感染的发病率高,革兰阴性杆菌仍为医院感染的主要病原体,对类风湿关节炎入院患者,要更加注重医院感染防控措施的实施,以降低医院感染的发病率。
OBJECTIVE To observe the clinical characteristics of nosocomial infections in the patients with rheumatoid arthritis（RA） and take positive prevention measures.METHODS The patients with RA who were admitted to the hospital between Sep 2006 and Nov 2011 were retrospectively investigated.Their basic information was registered in detail,and the statistical analysis of the acquired date was performed.RESULTS Of totally 1113 RA patients investigated,there were 226（238 case-times）patients who suffered from nosocomial infections with the infection rate of 20.29% and the case-time infection rate of 21.38%.The urinary tract and the lower respiratory tract were the predominant infection sites,accounting for 80.69%.All of the 238 case-times of patients were performed for the etiology examination,among which 234 cases were cultured positive,and totally 298 strains of pathogens were isolated,including 134（44.97%） strains of gram-negative bacteria,82（27.52%） strains of gram-positive bacteria,13（4.36%） strains of fungi,and 69（23.15%） strains of Mycoplasma,the pathogens varied in being isolated from the infection sites.CONCLUSION The incidence of nosocomial infections in the patients with RA is higher than the patients complicated with other diseases,the gram-negative bacilli remain dominant in the pathogens causing nosocomial infections.For the patients with RA,it is necessary to attach great importance to the implementation of the prevention measures so as to reduce the incidence of nosocomial infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第4期803-805,共3页
Chinese Journal of Nosocomiology
关键词
类风湿性关节炎
医院感染
临床特点
预防对策
Rheumatoid arthritis
Nosocomial infection
Clinical characteristic
Prevention countermeasure
