摘要
目的回顾性分析大连市2002～2011年新生儿疾病筛查情况。方法采用回顾性研究方法,分析2002～2011年各年度参加新生儿疾病筛查的所有助产机构的活产数、筛查人数、可疑阳性及确诊人数,从而计算大连市的筛查率及两种先天性疾病的检出率,并比较男女检出率的差别。结果 10年间大连市参加筛查的助产机构的活产数共382777人,筛查人数350 493人,平均筛查率91.57%。其中苯丙酮尿症确诊人数52人,检出率1.48/万;先天性甲状腺功能低下确诊134人,检出率3.82/万。两种疾病男女检出率比较差异均无显著性。结论大连市十年间新生儿疾病筛查平均筛查率91.5%,呈逐年上升趋势。苯丙酮尿症和先天性甲状腺功能低下两种疾病的男女检出率均无明显差别。对新生儿进行早期筛查、早期诊断、早期治疗是提高出生人口质量的重要措施。
Objective： To analyze the result of newborn screening in Dalian from 2002 to 2011.Methods： Retrospective study method was used to analyze the data of newborn screening.Including the number of live-born neonate born in Dalian midwifery institution,the number of newborns screened,the suspicious patients and patients.To calculate the screening rate and the detection rate of phenylketonuria（PKU） and congenital hypothyroidism（CH）.And to compare the difference of the detection rate in male and female.Result： During these 10 years,350 493 of 382 777 cases live-born have been screened.The average the screening rate is 91.57%.PKU was detected in 52 cases with detection rate of 0.148‰ and CH in 134 cases with detection rage of 0.382‰.There was no significant difference in detection rate between male and female.Conclusion： The average screening rate was 91.57% in the last ten years.The screening rate was increased year by year.There was no significant difference in detection rate of CH and PKU between male and female.The newborn disease screening is one of the effective methods to improve the birth health of newborns by early screening,early diagnostics and early treating.
出处
《中国优生与遗传杂志》
2013年第2期88-89,共2页
Chinese Journal of Birth Health & Heredity
