摘要
目的探讨急性ST段抬高心肌梗死(STEMI)患者发生恶性心律失常(MVA)的临床特点以及与炎性因子水平的关系。方法入选698例STEMI患者,均连续心电监护48h。根据患者是否发生MVA,分为MVA组46例和非MVA组652例,对2组资料进行单因素分析和多因素logistic回归分析。结果 2组性别、年龄、入院时收缩压、Killip分级、高敏C反应蛋白、白细胞、中性粒细胞、嗜酸性粒细胞、LVEF、左前降支病变和症状至球囊扩张时间等比较,差异有统计学意义(P<0.05,P<0.01)。高敏C反应蛋白、白细胞、中性粒细胞和嗜酸性粒细胞与MVA发生相关(P<0.05,P<0.01)。结论炎性因子水平升高是STEMI患者发生MVA的重要危险因素。
Objective To study the clinical characteristics of malignant arrhythmia in patients with ST-elevation myocardial infarction（STEMI） and their relation with inflammatory factors. Methods Six hundred and ninety-eight patients with STEMI were included in this study. The patients were monitored by BCG for 48 h in succession after admission and divided into malignant arrhythmia group（n=46） and non-malignant arrhythmia group（n=652）. Their baseline nature findings were analyzed by univariate analysis and multivariate logistic regression analysis. Results The differ- ence was significant in gender, age, systolic blood pressure at admission, Killip classification, hy- persensitive C-reactive protein, white blood cells, neutrophils, eosinophils, LVEF, left anterior de- scending artery lesion and time from symptom onset to balloon between the two groups（P〈0.05, P〈0.01）. The hypersensitive C-reactive protein, white blood ceils, neutrophils and eosinophils were related with the occurrence of malignant arrhythmia（P〈0.05,P〈0.01）. Conclusion Ele- vated level of inflammatory factors is an important risk factor for malignant arrhythmia in patients with STEMI.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2013年第2期143-146,共4页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词
心肌梗死
心律失常
心性
C反应蛋白质
白细胞
myocardial infarction arrhythmias, cardiac
C-reactive protein
leukocytes
