摘要
目的:探讨喉接触性肉芽肿的临床特点、诊断及治疗方法。方法:对15例喉接触性肉芽肿患者的临床资料进行回顾分析。其中13例全麻后在显微喉镜下用CO2激光切除肿物,术后激素雾化治疗2周;2例患者采用保守治疗,激素雾化的同时口服奥美拉唑(20 mg/d),持续治疗3个月。结果:所有患者的病理学表现均有明显肉芽组织、炎性反应细胞浸润和毛细血管增生。13例采取手术治疗的患者中有5例复发,行二次手术后随访1～5年均无复发;2例经保守治疗的患者随访1年病变未见明显好转。结论:喉接触性肉芽肿易复发,病因多样,应根据病因选择手术和(或)保守治疗,以提高治愈率并防止肉芽肿的复发。
Objective：To investigate the clinical features, diagnosis and treatment o~ Laryngea~ cu^lL~ s total of 15 patients with laryngeal contact granuloma were retrospectively analyzed. Results： Pathological characteristics of laryngeal contact granuloma were granulation tissue hyperplasia, inflammatory cells infiltration and capillary hyperpiasia. The follow-up period was 1 to 5 years. Among the 13 patients treated with operation, 5 patients had recurrence, who finally reco- vered after the second operation combined with non-surgical therapies. Two patients received non-surgical therapies only and the lesions remained stable after 1 year. Conclusions： Laryngeal contact granuloma has tendency of recurrence and various etio logical factors. Surgery combined with non-surgical therapies according to pathogenesis is necessary to prevent recurrence and improve cure rate.
出处
《中国临床医学》
2012年第6期672-673,共2页
Chinese Journal of Clinical Medicine
