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膀胱移行细胞癌组织中乳酸脱氢酶B亚基蛋白表达变化及意义 被引量：2

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摘要 目的观察膀胱移行上皮细胞癌(BTCC)中乳酸脱氢酶B亚基(LDHB)蛋白的表达变化,并探讨其意义。方法采用免疫组化SP法检测100例BTCC组织(BTCC组)及100例正常膀胱组织(对照组)中的LDHB蛋白,并分析LDHB蛋白表达与BTCC临床病理参数的关系。结果 BTCC组与对照组LDHB蛋白表达阳性分别为42、71例,两组相比,P<0.05。LDHB蛋白表达与BTCC临床分期和分化程度有关(P均<0.05),与患者年龄、性别、肿瘤直径无关(P均>0.05)。结论 LDHB蛋白在BTCC组织中的表达低于正常膀胱组织,其可能参与了BTCC的发病。
作者 张惟
机构地区 河南科技大学第一附属医院
出处 《山东医药》 CAS 2013年第2期82-83,共2页 Shandong Medical Journal
关键词 膀胱肿瘤 膀胱移行细胞癌 乳酸脱氢酶 乳酸脱氢酶B亚基
分类号 R737.11 [医药卫生—肿瘤]
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参考文献12

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同被引文献18

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山东医药
2013年 第2期

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