摘要
目的：评价后程调强适形放射治疗颈及胸上段食管癌的价值。方法：2005年1月-2010年8月,笔者所在医院行后程调强适形放疗治疗33例颈段及胸上段食管癌患者。前程采用常规放疗,T型野DT30Gy/15次后,食管病灶改为后程调强适形放疗,至总量56~70Gy,中位剂量62Gy,双锁骨上区预防照射剂量50Gy。结果：全组CR12例（36.3%）、PR20例（60.6%）。1、2年局控率为83.2%、71.6%,1、2年生存率为69.7%、62.4%,中位生存期22个月。结论：颈段及胸上段食管癌后程调强适形放疗疗效较好,治疗失败的主要原因为局部复发。
Objective：To evaluate the therapeutic effect of late-course intensity modulated radiotherapy in patients with cervical and upper thoracic esophageal carcinoma.Method：From January 2005 to August 2010,33 cases of cervical and upper thoracic esophageal carcinoma were treated with late-course intensity modulated radiotherapy.All patients underwent conventional radiotherapy of 30 Gy in 15 fractions with ＂T＂ shape radiation fields followed by late-course intensity modulated radiotherapy,with total dose of 56～70 Gy（median 62 Gy）.All patients received prophylactic irradiation of 50 Gy to the bilateral supraclavicular regions.Result：Complete response（CR）rate and partial response（PR） rate were 36.3%（12/33） and 60.6%（20/33）,respectively.The 1-year and 2-year local control rate were 83.2% and 71.6%,respectively.The 1-year and 2-year overall survival rate were 69.7% and 62.4%,respectively.The median overall survival was 22 months.Conclusion：Late-course intensity modulated radiotherapy appears to be a effective treatment for cervical and upper thoracic esophageal carcinoma,but local recurrence is still the main reason of treatment failure.
出处
《中国医学创新》
CAS
2012年第36期1-4,共4页
Medical Innovation of China
关键词
食管肿瘤
调强适形放疗
疗效
Esophageal carcinoma
Intensity modulated radiotherapy
Therapeutic effect
