摘要
目的:探讨尖吻蝮蛇毒的药理作用。方法:综述尖吻蝮蛇毒的化学成分、凝血作用、抗血栓作用、抗肿瘤机制及其他生理活性的最新研究进展。结果:研究表明尖吻蝮蛇毒在凝血、溶栓和肿瘤治疗中的应用越来越广泛,既有确切的疗效,又具有一定的不良反应。结论:对尖吻蝮蛇毒的化学成分及不良反应进行研究,观察其在人体内的代谢情况,提高其临床安全性和疗效仍将是今后重要的研究方向。
Objective：To carry out the progression of chemical composition,blood coagulation function,antithrombotic effect,antitumor mechanism and other physiological activity of Deinagkistrodon acutus snake venoms to provide the reference for clinical application and curative effect.Methods：To review the latest research progress of chemical composition,blood coagulation function,antithrombotic effect,antitumor mechanism and other physiological activity of Deinagkistrodon acutus snake venoms.Results：The study shows that the application in blood clotting,thrombolysis and oncotherapy is more and more widely as well as exact curative effect and great adverse reaction.Conclusion：The research of chemical composition,adverse reaction and body metabolism and improvement of clinical safety and efficacy of Deinagkistrodon acutus snake venoms will still be an important research direction in the future.
出处
《中医学报》
CAS
2013年第1期74-76,共3页
Acta Chinese Medicine
基金
安徽省教育厅自然科学基金项目(编号:KJ2012B066)
关键词
尖吻蝮蛇毒
凝血
抗血栓
抗肿瘤
deinagkistrodon acutus snake venoms
blood clotting
antithrombotic
antitumor
