摘要
目的探索磁共振成像(MRI)对恶性胸膜疾病的诊断价值。方法系统检索Medline、Embase、Cochrane Library、中国知网、维普中文科技期刊数据库(VIP)、万方等数据库,查找有关MRI在良恶性胸膜疾病诊断价值的文献。采用诊断性试验准确性质量评价工具(QUADAS)评价纳入文献的质量,应用Meta-DiSc 1.4软件对纳入研究进行综合定量评价,并绘制综合受试者工作特征(SROC)曲线,对诊断性试验的准确性进行评估。结果共纳入6篇文献,其中4篇英文文献,2篇中文文献;3篇文献QUADAS评分≥10分。异质性检验未发现异质性。Meta分析计算MRI诊断恶性胸膜疾病的敏感度、特异度、阳性似然比、阴性似然比、诊断优势比的汇总值分别为0.96〔95%CI(0.91,0.98)〕、0.88〔95%CI(0.80,0.94)〕、7.09〔95%CI(4.31,11.66)〕、0.05〔95%CI(0.03,0.11)〕、101.06〔95%CI(39.41,259.21)〕。SROC曲线下面积(AUC)为0.8582。结论 MRI检查对于诊断恶性胸膜疾病具有较高的敏感度,具有良好的诊断价值。
Objective To investigate the value of MRI in the diagnosis of malignant pleural diseases. Methods Qualified studies on evaluation of MRI in the diagnosis of malignant pleural diseases were retrieved from The Medline,Embase,Cochrane Library,China National Knowledge Infrastructure（CNKI） databases,WanFang Database and VIP Database.The methodological quality of each study was evaluated by QUADAS.Statistical analyses were performed by employing Meta-DiSc 1.4 software.Meta-analyses of the reported accuracy of each study were performed and summary receiver qperating characteristic（SROC） curve was drawn. Results Six studies,including 4 English and 2 Chinese,met the inclusion criteria for the analysis.There were 3 studies with QUADASA scores more than 10（including 10）.Heterogeneity test did not find significant heterogeneity among included studies.The sensitivity was 0.96（95%CI（0.91,0.98））,the specificity was 0.88（95%CI（0.80,0.94））,the positive likelihood ratio was 7.09（95%CI（4.31,11.66））,negative likelihood ratio was 0.05（95%CI（0.03,0.11））the diagnostic odds ratio was 101.06（95%CI（39.41,259.21）） and the AUC of SROC was 0.8582. Conclusion MRI is sensitive and has good value in the diagnosis of malignant pleural diseases.
出处
《中国全科医学》
CAS
CSCD
北大核心
2013年第3期292-294,共3页
Chinese General Practice
关键词
磁共振成像
胸膜疾病
诊断
鉴别
META分析
Magnetic resonance imaging
Pleural diseases
Diagnosis
differential
Meta-analysis
