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温胆汤对湿热质脑梗死患者二级预防的临床研究 被引量:5

Clinical research of Wendan decoction on the secondary prevention of cerebral infarction with damp heat constitution
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摘要 目的观察温胆汤对湿热质脑梗死患者二级预防的临床疗效。方法将110例湿热质脑梗死患者随机分为2组,对照组55例予阿司匹林肠溶片治疗,治疗组55例在对照组治疗基础上应用温胆汤治疗。2组均治疗6个月。观察2组疗效,比较治疗前后临床神经功能缺损评分、日常生活活动能力(ADL)量表(Barthel指数)、中医证候评分的变化。结果治疗组治疗后临床神经功能缺损评分较本组治疗前、对照组治疗后均降低(P<0.05,P<0.01)。治疗组治疗后Barthel指数较本组治疗前、对照组治疗后均升高(P<0.05,P<0.01)。治疗组治疗后中医证候评分较本组治疗前、对照组治疗后均降低(P<0.05,P<0.01)。治疗组总有效率89.09%,对照组总有效率76.36%,2组总有效率比较差异有统计学意义(P<0.05),治疗组疗效优于对照组。结论温胆汤对湿热质脑梗死患者二级预防有一定的疗效,是临床预防脑梗死安全有效的方法之一。 Objective To observe clinical effect of Wendan decoction on the secondary prevention of cerebral infarction with damp heat constitution.Methods 110 patients with cerebral infarction with damp heat constitution were randomly divided into two groups.55 cases in control group were treated by aspirin enteric-coated tablets.55 cases in treatment group were treated by Wendan decoction on the basis of control group's treatment.The course was six months in two groups.The changes of clinical neurological deficit scores,activities of daily living(ADL) scale(Barthel Index),and traditional Chinese medicine syndrome score before and after treatment were compared.Results Clinical neurological deficit scores and traditional Chinese medicine syndrome score after treatment in treatment group was decreased as compared with that before treatment in treatment group and after treatment in control group(P〈0.05,P〈0.01).Barthel Index after treatment in treatment group was increased as compared with that before treatment in treatment group and after treatment in control group(P〈0.05,P〈0.01).The total effective rate in treatment group(89.00%) was higher than that in control group(76.36%,P〈0.05).Conclusion Wendan decoction has a definite effect on the secondary prevention of cerebral infarction with damp heat constitution,and it is a safer and more effective method of preventing cerebral infarction.
出处 《河北中医》 2012年第11期1645-1647,共3页 Hebei Journal of Traditional Chinese Medicine
基金 河北省石家庄市科技局资助项目(编号:091461303)
关键词 脑梗死 温胆汤 中西医结合疗法 Cerebral infarction Wendan decoction Combined therapy of Chinese and Western medicine
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