摘要
目的探讨盐酸多西环素联合阿奇霉素治疗女性生殖道支原体(UU)感染的临床疗效。方法将2010年1月-2012年1月在合浦妇幼保健院门诊的314例女性生殖道UU感染的患者,年龄19～47岁,平均38岁,按照治疗方法的不同分为治疗组155例和对照组159例,对照组单纯采用阿奇霉素治疗,治疗组在对照组的基础上采用盐酸多西环素治疗,比较两组的UU转阴率、症状消失情况及不良反应。结果治疗组的UU转阴率为90.96%,显著高于对照组的61.63%(P<0.05)。治疗组泌尿系感染症状外阴不适的消失比率显著高于对照组(P<0.05)。两组患者的不良反应的发生率差异无统计学意义(P>0.05)。结论盐酸多西环素联合阿奇霉素能够快速消除UU感染,缓解患者的临床症状,不良反应少,值得临床推广。
Objective To explore the effect of doxycycline hydrochloride with azithromycin on ureaplasma urealyticum in fe-male genital tract infection. Methods All 314 women with UU aged 19 to 47 years（ mean 38 years） from January 2010 to Janu-ary in our hospital were divided into two groups in accordance with the therapeutic methods. The control group （ 159 cases ） re-ceived azithromycin ,while the experimental group（ 155 cases） received doxyeycline hydrochloride and azithromyein. The change of UU positive rate, disappear of symptoms and adverse reactions were compared between the two groups. Results UU clearance rate was 90.96% in the treatment group, and was higher than 61.63% in the control group（P 〈 0.05 ）. The rate of vulva discom- fort decreased obviously in the experimental group as compared to the control group（ P 〈 0.05 ）. The difference in the rate of ad-verse effects was not significant （ P 〉 0.05 ）. Conclusion The treatment with doxycycline hydrochloride and azithromycin can quickly remove UU infection, relieve the clinical symptoms, and the side effect is also slight.
出处
《中华全科医学》
2013年第2期242-243,共2页
Chinese Journal of General Practice
关键词
盐酸多西环素
阿奇霉素
女性生殖道
支原体感染
Doxycycline hydrochloride
Azithromycin
Infection of female reproductive tract
Ureaplasma urealyticum
