摘要
目的通过对急性心衰(AHF)患者床旁检测氨基末端B型钠尿肽原(NT-proBNP),探讨NT-proBNP对AHF患者早期风险评估的意义。方法选择AHF患者113例,根据在院期间是否发生心血管事件分为无事件组、事件组,并于就诊即刻检测NT-proBNP,研究其与AHF患者发生心血管事件的联系。结果 AHF患者在院期间事件组的NT-proB-NP高于无事件组(P<0.01)。应用受试者工作特征(ROC)曲线分析NT-proBNP评价AHF患者在院期间发生心血管事件,计算曲线下面积(AUC)为0.871,最佳临界点是15 000 pg/ml。结论 NT-proBNP对AHF患者早期风险评估是有意义的。
Objective To explore the clinical value of the amino-terminal pro-B-type natriuretic peptide (NT-proBNP) by Point of care test(POCT) in the early risk assessment for patients with acute heart failure (AHF). Methods A total 113 patients with AHF were divided into cardiovascular events group and non-cardiovascular event group. NT-proBNP in both groups was de- tected at admission. The relationship between NT-proBNP level and the occurrence of cardiovascular in patients with AHF were e-valuated. Results The NT-proBNP level in the cardiovascular event group was significant higher than that in the non-cardiovas-cular events group(P 〈0.01 ). The receiver operating characteristic(ROC) curve showed that the area under the curve (AUC) for NT-proBNP was 0.871 ,and the cutoff point was 15 000 pg/ml. Conclusion NT-proBNP level is meaningful to early risk as- sessment in patients with AHF.
出处
《中华全科医学》
2013年第2期194-195,共2页
Chinese Journal of General Practice
关键词
床旁检测
钠尿肽
急性心衰
评估
Point of care test
Amino-terminal pro-B-type natriuretic peptide
Heart failure
Assessment