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乳腺浸润性导管癌组织学分级与预后关系的研究 被引量:2

Study of histological grading and prognosis in breast invasive ductal carcinoma
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摘要 目的 :探讨乳腺浸润性导管癌的组织学分级与预后的关系。方法 :对有 5年以上随访资料的 86例乳腺浸润性导管癌按腺管形成 ,核的异型性和核分裂相进行组织学分级。结果 :在浸润性导管癌中 ,Ⅰ级 (2 6例 )、Ⅱ级 (42例 )、Ⅲ级 (1 8例 )的 5年生存率分别为 80 8% (2 1例 )、57 1 % (2 4例 )、44 4% (8例 ) ,Ⅰ、Ⅱ级之间和Ⅰ、Ⅲ级之间分别有显著性差异 (P <0 0 5)。结论 :在浸润性导管癌中 ,组织学分级是一个较好的预后指标 ;结合腋下淋巴结情况 ,对判断预后更有意义。 Objective:To study the relationship between histological grading and prognosis in breast invasive ductal carcinoma (IDC).Methods:According to the formation of glandular structure,atypia of nucleus and mitosis,86 cases of breast IDC with more than 5-year follow-up were assessed for grade Ⅰ,Ⅱ and Ⅲ.Results:The 5-year survival rates of IDC grade Ⅰ,Ⅱ and Ⅲ were 80·8%,57 1% and 44 4% respectively.There was significant difference between grade Ⅰ and Ⅱ,so was grade Ⅰ and Ⅲ (P<0 05).Conclusions:Histological grading of IDC is a good prognostic factor,and has an important significance in the evaluation of prognosis combining with axillary lymph-node metastasis.
作者 徐建新 吕翔
出处 《中国冶金工业医学杂志》 2000年第3期131-134,共4页 Chinese Medical Journal of Metallurgical industry
关键词 组织学分级 预后 乳腺癌 浸润性导管癌 Breast carcinoma Histological grading Prognosis
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参考文献4

  • 1Daris BW,Gelber RD,Goldhirsch A,et al.Prognostic significance of tumor grade in clinical trials of adjuvant therapy for breast cancer with axillary lymphnode metastasis[].Cancer.1986
  • 2Le Doussal V,Tubiana-Hulin M,Friedman S,et al.Prognostic value of histologic grade nuclear components of Scarft-Bloom-Richardson(SBR)[].Cancer.1989
  • 3Elston CW,Ellis IO.Pathological prognostic factors in breast cancer.I The value of histological grade in breast cancer: experience from a large study with long-term follow-up[].Histopathology.1991
  • 4Hutter RVP.The role of the pathologist in breast cancer management[].Cancer.1990

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