摘要
目的 :观察参附注射液对呼吸衰竭患者机械通气时间的干预作用。方法 :选取2008年1月—2011年12月入住我院ICU的120例属于肺肾气虚证的呼吸衰竭患者,按照随机数字表法随机分为对照组与治疗组,每组患者均为60例。对照组给予常规西医治疗,治疗组在对照组的基础上加用参附注射液,疗程21 d。比较两组临床疗效,具体观察指标包括:血清前白蛋白(PALB)、超敏C反应蛋白(HSCRP)、动脉血氧分压(PaO2)、氧合指数(PaO2/FiO2)、机械通气时间(d)。结果 :总有效率治疗组高于对照组,症状、体征改善情况治疗组优于对照组,差异均有统计学意义(P<0.05)。结论 :参附注射液可以改善呼吸衰竭患者血清前白蛋白、超敏C反应蛋白水平,改善氧合,缩短机械通气时间。
Objective:To observe intervention of Shenfu Injection on the duration of mechanical ventilation in patients with respiratory failure. Method: 120 eases with respiratory failure of lung Qi deficiency staying in the ICU of our hospital from 2009 January to 2011 December were chosen and divided into a control group and a treatment group according to the random number table, each group had 60 cases. The control group was given conventional western medicine and the treatment group used Shenfu Injection on the base of the control group with a 21-day treatment. Results: The total effective rate in the treatment group was higher than that in the control group and the differences were statistically significant ( P〈0.05 ). Conclusion:Shenfu Injection can improve serum albumin and high-sensitivity C-reactive protein levels of the patients with respiratory failure, improve oxygenation, and shorten the duration of mechanical ventilation.
出处
《辽宁中医药大学学报》
CAS
2013年第2期160-162,共3页
Journal of Liaoning University of Traditional Chinese Medicine
关键词
参附注射液
呼吸衰竭
机械通气
临床研究
Shenftl Injection
respiratory failure
mechanical ventilation
clinical research