摘要
目的建立香平茶清排铅颗粒的质量标准。方法采用化学方法对香平茶清排铅颗粒中的维生素C进行鉴别;采用薄层色谱法(TLC)对该处方中的绿茶提取物、菊花提取物进行鉴别;采用高效液相色谱法(HPLC)测定处方中主要成分绿原酸和表儿茶素的含量。结果化学方法可鉴别维生素C;TLC法可鉴别出处方中绿茶提取物、菊花提取物;HPLC法测定绿原酸、表儿茶素的含量,线性良好,方法准确可靠,可以较好地控制该制剂的质量。结论所建立的方法准确可靠、灵敏度高、专属性强,可有效控制香平茶清排铅颗粒的质量。
Objective To establish a quality standard for Xiangping chaqing paiqian granules. Methods Chemical methods were used to identify vitamin C in the granules. TLC methods were used to identify green tea extracts and chrysanthemum extracts. Chlorogenic acid and catechin were assayed by HPLC. Results Vitamin C could be identified by chemical method, and green tea ex- tracts and chrysanthemum extracts could be identified by TLC. The content of chlorogenic acid and catechin could be assayed by HPLC. Conclusion The methods were proved to be reliable, good sensitivity and high specificity, which could be used in quality con- trol of Xiangping chaqing paiqian granules.
出处
《药学实践杂志》
CAS
2013年第1期57-60,共4页
Journal of Pharmaceutical Practice
