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脑梗死患者血浆同型半胱氨酸变化及叶酸、维生素B_(12)的干预作用 被引量:2

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摘要 同型半胱氨酸是一种含硫基的氨基酸。它由蛋氨酸去甲基化而来,是蛋氨酸分解过程中产生的中间产物。近年来研究表明,同型半胱氨酸水平升高是动脉粥样硬化性血管病、动静脉血栓栓塞及周围血管性疾病的一个重要的独立危险因素,因此,同型半胱氨酸和脑梗死的关系日益受到关注。为此,我们对脑梗死患者血浆同型半胱氨酸水平进行测定,并以叶酸和维生素B12进行干预,现将结果报告如下。
机构地区 衢州市中医医院
出处 《中国初级卫生保健》 2012年第12期120-121,共2页 Chinese Primary Health Care
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  • 1黄海威,郭明辉,黄家星,林锐金,张颖,陈亚利.1020名社区人群同型半胱氨酸水平的调查和相关分析[J].中华流行病学杂志,2006,27(8):721-724. 被引量:42
  • 2McCully K S. Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis[J]. Am J Pathol, 1969, 56 (1): 111-28.
  • 3Zhang Wei-li, Sun Kai, Chen Jin-xing, et al. High plasma homo- cysteine levels contribute to the risk of stroke recurrence and all-cause mortality in a large prospective stroke population[J]. Clin Sci(Lond), 2010, 118(3): 187-94.
  • 4Li Z, Sun L, Zhang H, et al. Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylene- tetrabydrofolate reductase gene C677T Polymorphism was a risk factor for thrombotic stroke: a muhicenter case-control study in China[J]. Stroke, 2003, 34(9): 2085-2090.
  • 5Towfighi A, Markovic D, Ovbiagele B. Pronounced association of elevated serum homocysteine with stroke in subgroups of individu- als. a nationwide study[J]. J Neurol Sci, 2010, 298(1-2): 153-157.
  • 6Jacques P, Rosnbery I H, Selhub J, et al. Serum total homocyste- ine concentration in adolescent and adult American: results from the Third National Health and Nutrition Examination Survey[J]. Am J Clin Nutr, 1999. 69(3): 482-489.
  • 7Bostom A G, Silbershatz H, Rosenberg I H, et al. Nonfasting Plas- ma total homocysteine levels and all-cause and cardiovascular dis- ease mortality in elderly Framingham men and women[J]. Arch In- tern Med, 1999, 159(10): 1077-80.
  • 8Rolita L, Holtzer R, Wang C, et al. Homocysteine and mobility in older adults[J]. J Am Geriatr Soc, 2010, 58(3): 545-550.
  • 9Lim U, Cassano P A. Homocysteine and blood pressure in the Third National Health and Nutrition Examination Survey[J]. Am J Epidemiol, 2002, 156(12): 1105.
  • 10Sutton-Tyrrell K, Bostom A, Selhub J, et al. High homocysteine level are independently related to isolated systolic hypertension in older adults [J]. Circulation, 1997, 96(6): 1745.

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